Publications of Andrea Musacchio

Faesen, A. C.; Thanasoula, M.; Maffini, S.; Breit, C.; Müller, F.; Van Gerwen, S.; Bange, T.; Musacchio, A.: Basis of catalytic assembly of the mitotic checkpoint complex. Nature 542 (7642), pp. 498 - 502 (2017)

Huis in´t Veld, P. J.; Jeganathan, S.; Petrovic, A.; Singh, P.; John, J.; Krenn, V.; Weissmann, F.; Bange, T.; Musacchio, A.: Molecular basis of outer kinetochore assembly on CENP-T. eLife 5, p. 5:e21007 (2016)

Pan, D.; Klare, K.; Petrovic, A.; Take, A.; Walstein, K.; Singh, P.; Rondelet, A.; Bird, A. W.; Musacchio, A.: CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading. eLife 6, e23352, pp. e23352:1 - e23352:62 (2016)

Petrovic, A.; Keller, J.; Liu, Y.; Overlack, K.; John, J.; Dimitrova, Y. N.; Jenni, S.; Van Gerwen, S.; Stege, P.; Wohlgemuth, S. et al.; Rombaut, P.; Herzog, F.; Harrison, S. C.; Vetter, I. R.; Musacchio, A.: Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. Cell 167 (4), pp. 1028 - 1040 (2016)

Weir, J. R.; Faesen, A. C.; Klare, K.; Petrovic, A.; Basilico, F.; Fischböck, J.; Pentakota, S.; Keller, J.; Pesenti, M.; Pan, D. et al.; Vogt, D.; Wohlgemuth, S.; Herzog, F.; Musacchio, A.: Insights from biochemical reconstitution into the architecture of human kinetochores. Nature 537 (7619), pp. 249 - 253 (2016)

Borisy, G.; Heald, R.; Howard, J.; Janke, C.; Musacchio, A.; Nogales, E.: Microtubules: 50 years on from the discovery of tubulin. Nature Reviews Molecular Cell Biology 17 (5), pp. 322 - 328 (2016)

Friese, A.; Faesen, A. C.; Huis in´t Veld, P. J.; Fischböck, J.; Prumbaum, D.; Petrovic, A.; Raunser, S.; Herzog, F.; Musacchio, A.: Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin. Nature Communications 7, 11407, pp. 1 - 12 (2016)

Pesenti, M.; Weir, J. R.; Musacchio, A.: Progress in the structural and functional characterization of kinetochores. Current Opinion in Structural Biology 37, pp. 152 - 163 (2016)

Liu, Y.; Petrovic, A.; Rombaut, P.; Mosalaganti, S.; Keller, J.; Raunser, S.; Herzog, F.; Musacchio, A.: Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster. Open Biology 6 (2), pp. 1 - 11 (2016)

O’Connor, A.; Maffini, S.; Rainey, M. D.; Kaczmarczyk, A.; Gaboriau, D.; Musacchio, A.; Santocanale, C.: Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint. Biology Open 5 (1), pp. 11 - 19 (2015)

Breit, C.; Bange, T.; Petrovic, A.; Weir, J. R.; Müller, F.; Vogt, D.; Musacchio, A.: Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1. PLoS One 10 (12), pp. e0144673:1 - e0144673:24 (2015)

Musacchio, A.: The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics. Current Biology 25 (20), pp. R1002 - R1018 (2015)

Krenn, V.; Musacchio, A.: The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling. Frontiers in Oncology 5, 225, pp. 225:1 - 225:18 (2015)

Klare, K.; Weir, J. R.; Basilico, F.; Zimniak, T.; Massimiliano, L.; Ludwigs, N.; Herzog, F.; Musacchio, A.: CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores. The Journal of Cell Biology: JCB 210 (1), pp. 11 - 22 (2015)

Meyer, R.; Faesen, A.; Vogel, K.; Jeganathan, S.; Musacchio, A.; Niemeyer, C. M.: DNA-Directed Assembly of Capture Tools for Constitutional Studies of Large Protein Complexes. Small 11 (22), pp. 2669 - 2674 (2015)

Musacchio, A.: CHECKPOINT PROTEINS: Closing the Mad2 cycle. eLife, pp. 4:e08283:1 - 4:e08283:3 (2015)

Tachiwana, H.; Müller, S.; Blümer, J.; Klare, K.; Musacchio, A.; Almouzni, G.: HJURP Involvement in De Novo CenH3CENP-A and CENP-C Recruitment. Cell Reports 11 (1), pp. 22 - 32 (2015)

Altenfeld, A.; Wohlgemuth, S.; Wehenkel, A.; Vetter, I. R.; Musacchio, A.: Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the human Rod-Zwilch-ZW10 (RZZ) complex. Acta Crystallographica Section F: Structural Biology Communications 71 (Part 4), pp. 438 - 442 (2015)

Faesen, A.; Musacchio, A.: The (Phospho) Needle in the (MELT) Haystack. Molecular Cell 57 (5), pp. 765 - 766 (2015)

Overlack, K.; Primorac, I.; Vleugel, M.; Krenn, V.; Maffini, S.; Hoffmann, I.; Kops, G. J. P. L.; Musacchio, A.: A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint. eLife, pp. 05269:1 - 05269:52 (2015)