Publications of Alfred Wittinghofer
All genres
Journal Article (246)
Journal Article
31 (20), 1, pp. 4085 - 4094 (2012)
Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119. The EMBO Journal
Journal Article
109 (26), 1, pp. 10322 - 10327 (2012)
Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
14, 1, pp. 148 - 158 (2012)
The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins. Nature Cell Biology
Journal Article
90 (11), 1, pp. 934 - 943 (2011)
Rho proteins of plants - Functional cycle and regulation of cytoskeletal dynamics. European Journal of Cell Biology
Journal Article
7, 1, pp. 942 - 949 (2011)
Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo. Nature Chemical Biology
Journal Article
411 (4), 1, pp. 808 - 822 (2011)
Dimeric Plant RhoGAPs Are Regulated by Its CRIB Effector Motif to Stimulate a Sequential GTP Hydrolysis. Journal of Molecular Biology
Journal Article
30 (20), 1, pp. 4185 - 4197 (2011)
Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity. The EMBO Journal
Journal Article
95, Preprint, pp. 1 - 39 (2011)
The unique plant RhoGAPs are dimeric and contain a CRIB motif required for affinity and specificity towards cognate small G proteins. Biopolymers
Journal Article
80, 1, pp. 943 - 971 (2011)
Structure-Function Relationships of the G Domain, a Canonical Switch Motif. Annual Review of Biochemistry
Journal Article
392 (8-9), 1, pp. 791 - 797 (2011)
Structural and biochemical properties of Sept7, a unique septin required for filament formation. Biological Chemistry
Journal Article
1 (3), 1, pp. 133 - 141 (2010)
GTPase activity of Di-Ras proteins is stimulated by Rap1GAP proteins. Small Gtpases
Journal Article
403 (5), 1, pp. 529 - 545 (2010)
Actin Filament Bundling and Different Nucleating Effects of Mouse Diaphanous-Related Formin FH2 Domains on Actin/ADF and Actin/Cofilin Complexes. Journal of Molecular Biology
Journal Article
32 (1), 1, pp. 33 - 43 (2010)
Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. Human Mutation
Journal Article
49 (35), 1, pp. 6090 - 6095 (2010)
Synthesis of the Rheb and K-Ras4B GTPases. Angewandte Chemie International Edition
Journal Article
285 (22), 1, pp. 16991 - 17000 (2010)
Stabilization of G Domain Conformations in the tRNA-modifying MnmE-GidA Complex Observed with Double Electron Electron Resonance Spectroscopy. Journal of Biological Chemistry
Journal Article
141 (5), 1, pp. 812 - 821 (2010)
The Structure of an Arf-ArfGAP Complex Reveals a Ca2+ Regulatory Mechanism. Cell
Journal Article
21 (6), 1, pp. 936 - 945 (2010)
A Rap/Phosphatidylinositol 3-Kinase Pathway Controls Pseudopod Formation. Molecular Biology of the Cell
Journal Article
122 (35), 1, pp. 6226 - 6231 (2010)
Synthesis of the Rheb and K-Ras4B GTPases. Angewandte Chemie
Journal Article
42 (1), 1, pp. 27 - 29 (2010)
A restricted spectrum of NRAS mutations causes Noonan syndrome. Nature Genetics
Journal Article
29 (14), 1, pp. 2276 - 2289 (2010)
Regulation of dynamic polarity switching in bacteria by a Ras-like G-proein and its cognate GAP. EMBO Journal