Publications of Andrea Musacchio

Musacchio, A.: Spindle assembly checkpoint: the third decade. Philosophical Transactions of the Royal Society B-Biological Sciences 366 (1584), 1, pp. 3595 - 3604 (2011)

Balzano, D.; Santaguida, S.; Musacchio, A.; Villa, F.: A General Framework for Inhibitor Resistance in Protein Kinases. Chemistry & Biology 18 (8), 1, pp. 966 - 975 (2011)

Musacchio, A.: Travel Notes from the Equatorial Circle. Cell 146 (4), 1, pp. 499 - 501 (2011)

Perrakis, A.; Musacchio, A.; Cusack, S.; Petosa, C.: Investigating a macromolecular complex: the toolkit of methods. Journal of Structural Biology 175 (2), 1, pp. 106 - 112 (2011)

Alexander, J.; Lim, D.; Joughin, B. A.; Hegemann, B.; Hutchins, J. R. A.; Ehrenberger, T.; Ivins, F.; Sessa, F.; Hudecz, O.; Nigg, E. A. et al.; Fry, A. M.; Musacchio, A.; Stukenberg, P. T.; Mechtler, K.; Peters, J.-M.; Smerdon, S. J.; Yaffe, M. B.: Spatial Exclusivity Combined with Positive and Negative Selection of Phosphorylation Motifs Is the Basis for Context-Dependent Mitotic Signaling. Science Signaling 4 (179), 1, pp. ra42-1 - ra42-15 (2011)

Maspero, E.; Mari, S.; Valentini, E.; Musacchio, A.; Fish, A.; Pasqualato, S.; Polo, S.: Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation. EMBO Reports 12 (4), 1, pp. 342 - 349 (2011)

Screpanti, E.; De Antoni, A.; Alushin, G. M.; Petrovic, A.; Melis, T.; Nogales, E.; Musacchio, A.: Direct Binding of CENP-C to the Mis12 Complex Joins the Inner and Outer Kinetochore. Current Biology 21, 1, pp. 391 - 398 (2011)

Maure, J.-F.; Komoto, S.; Oku, Y.; Mino, A.; Pasqualato, S.; Natsume, K.; Clayton, L.; Musacchio, A.; Tanaka, T. U.: The Ndc80 Loop Region Facilitates Formation of Kinetochore Attachment to the Dynamic Microtubule Plus End. Current Biology 21 (3), 1, pp. 207 - 213 (2011)

Mattiuzzo, M.; Vargiu, G.; Totta, P.; Fiore, M.; Ciferri, C.; Musacchio, A.; Degrassi, F.: Abnormal Kinetochore-Generated Pulling Forces from Expressing a N-Terminally Modified Hec1. PLoS ONE 6 (1), e16307 (2011)

Santaguida, S.; Vernieri, C.; Villa, F.; Ciliberto, A.; Musacchio, A.: Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction. The EMBO Journal 30 (8), 1, pp. 1508 - 1519 (2011)

Çivril, F.; Wehenkel, A.; Giorgi, F. M.; Santaguida, S.; Di Fonzo, A.; Grigorean, G.; Ciccarelli, F. D.; Musacchio, A.: Structural Analysis of the RZZ Complex Reveals Common Ancestry with Multisubunit Vesicle Tethering Machinery. STRUCTURE 18 (5), pp. 616 - 626 (2010)

Hewitt, L.; Tighe, A.; Santaguida, S.; White, A. M.; Jones, C. D.; Musacchio, A.; Green, S.; Taylor, S. S.: Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex. JOURNAL OF CELL BIOLOGY 190 (1), pp. 25 - 34 (2010)

Musacchio, A.: Cell Cycle: Deconstructing Tension. CURRENT BIOLOGY 20 (15), pp. R634 - R637 (2010)

Petrovic, A.; Pasqualato, S.; Dube, P.; Krenn, V.; Santaguida, S.; Cittaro, D.; Monzani, S.; Massimiliano, L.; Keller, J.; Tarricone, A. et al.; Maiolica, A.; Stark, H.; Musacchio, A.: The MIS12 complex is a protein interaction hub for outer kinetochore assembly. JOURNAL OF CELL BIOLOGY 190 (5), pp. 835 - 852 (2010)

Santaguida, S.; Tighe, A.; D'Alise, A. M.; Taylor, S. S.; Musacchio, A.: Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. JOURNAL OF CELL BIOLOGY 190 (1), pp. 73 - 87 (2010)

Amabile, G.; D'Alise, A. M.; Iovino, M.; Jones, P.; Santaguida, S.; Musacchio, A.; Taylor, S.; Cortese, R.: The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts. CELL DEATH AND DIFFERENTIATION 16 (2), pp. 321 - 330 (2009)

Nezi, L.; Musacchio, A.: Sister chromatid tension and the spindle assembly checkpoint. CURRENT OPINION IN CELL BIOLOGY 21 (6), pp. 785 - 795 (2009)

Santaguida, S.; Musacchio, A.: The life and miracles of kinetochores. EMBO JOURNAL 28 (17), pp. 2511 - 2531 (2009)

Villa, F.; Capasso, P.; Tortorici, M.; Forneris, F.; de Marco, A.; Mattevi, A.; Musacchio, A.: Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106 (48), pp. 20204 - 20209 (2009)

Andersen, C. B.; Wan, Y.; Chang, J. W.; Riggs, B.; Lee, C.; Liu, Y.; Sessa, F.; Villa, F.; Kwiatkowski, N.; Suzuki, M. et al.; Nallan, L.; Heald, R.; Musacchio, A.; Gray, N. S.: Discovery of selective aminothiazole aurora kinase inhibitors. ACS CHEMICAL BIOLOGY 3 (3), pp. 180 - 192 (2008)