Publications of Tobias Restle

Kalinin, S.; Peulen, T.; Sindbert, S.; Rothwell, P. J.; Berger, S.; Restle, T.; Goody, R. S.; Gohlke, H.; Seidel, C. A. M.: A toolkit and benchmark study for FRET-restrained high-precision structural modeling. Nature Methods 9 (12), 1, pp. 1218 - 1225 (2012)

Cramer, J.; Rangam, G.; Marx, A.; Restle, T.: Varied Active-Site Constraints in the Klenow Fragment of E. coli DNA Polymerase I and the Lesion-Bypass Dbh DNA Polymerase. ChemBioChem 9 (8), 1, pp. 1243 - 1250 (2008)

Cramer, J.; Jaeger, J.; Restle, T.: Biochemical and Pre-Steady-State Kinetic Characterization of the Hepatitis C Virus RNA Polymerase (NS5BΔ21,HC-J4). Biochemistry 45 (11), 1, pp. 3610 - 3619 (2006)

Cramer, J.; Restle, T.: Pre-steady-state Kinetic Characterization of the DinB Homologue DNA Polymerase of Sulfolobus solfataricus. Journal of Biological Chemistry 280 (49), 1, pp. 40552 - 40558 (2005)

Dumitru, G. L.; Groemping, Y.; Klostermeier, D.; Restle, T.; Deuerling, E.; Reinstein, J.: DafA Cycles Between the DnaK Chaperone System and Translational Machinery. Journal of Molecular Biology 339 (5), 1, pp. 1179 - 1189 (2004)

Rothwell, P. J.; Berger, S.; Kensch, O.; Felekyan, S.; Antonik, M.; Wöhrl, B. M.; Restle, T.; Goody, R. S.; Seidel, C. A. M.: Multiparameter single-molecule fluorescence spectroscopy reveals heterogeneity of HIV-1 reverse transcriptase:primer/template complexes. Proceedings of the National Academy of Sciences of the USA 100 (4), 1, pp. 1655 - 1660 (2003)

Cramer, J.; Strerath, M.; Marx, A.; Restle, T.: Exploring the effects of active site constraints on HIV-1 reverse transcriptase DNA polymerase fidelity. Journal of Biological Chemistry 277 (46), 1, pp. 43593 - 43598 (2002)

Strerath, M.; Cramer, J.; Restle, T.; Marx, A.: Implications of active site constraints on varied DNA polymerase selectivity. Journal of the American Chemical Society 124 (38), 1, pp. 11230 - 11231 (2002)

Chaloin, L.; Lehmann, M. J.; Sczakiel, G.; Restle, T.: Endogenous expression of a high-affinity pseudoknot RNA aptamer suppresses replication of HIV-1. Nucleic Acids Research 30 (18), 1, pp. 4001 - 4008 (2002)

Grohmann, D.: Entwicklung antiviraler Strategien am Beispiel der HIV-1 Reversen Transkriptase. Dissertation, Heinrich-Heine-Universität, Düsseldorf (2006)

Cramer, J.: Funktionelle Charakterisierung der RNA-abhängigen RNA-Polymerase des Hepatitis-C-Virus: Untersuchung molekularer Mechanismen der Substratspezifität von DNA-abhängigen DNA-Polymerasen. Dissertation, Ruhr-Universität, Bochum (2004)

Restle, T.: Die reverse Transkriptase des menschlichen Immundefizienz Virus; Molekulare Details zum Reaktionsmechanismus des Enzyms und strategische Konzepte zur Hemmung der HIV Replikation. Habilitation, Witten/Herdecke (2001)