Selected Publications 2021

Ultrarapid cryo-arrest of living cells on a microscope enables multiscale imaging of out-of-equilibrium molecular patterns

Ultrarapid cryo-arrest of living cells on a microscope enables multiscale imaging of out-of-equilibrium molecular patterns

Huebinger J, Grecco H, Masip ME, Christmann J, Fuhr GR, Bastiaens PIH (2021) [more]
Small molecule modulation of the&nbsp;<em>Drosophila</em>&nbsp;Slo channel elucidated by cryo-EM

Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM

Raisch T, Brockmann A, Ebbinghaus-Kintscher U, Freigang J, Gutbrod O, Kubicek J, Maertens B, Hofnagel O, Raunser S (2021) [more]
Molecular architecture of black widow spider neurotoxins

Molecular architecture of black widow spider neurotoxins

Chen M, Blum D, Engelhard L, Raunser S , Wagner R & Gatsogiannis C (2021) [more]
Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly

Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly

van den Boom J, Kueck AF, Kravic B, Müschenborn H, Giesing M, Pan D, Kaschani F, Kaiser M, Musacchio A, Meyer H (2021) [more]
High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism.

High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism.

Pospich S, Sweeney HL, Houdusse A, Raunser S (2021). eLife [more]
&nbsp;Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens

 Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens

Belyy A, Merino F, Mechold U, Raunser S (2021), Nature Communications [more]
Exploiting non-covalent interactions in selective carbohydrate synthesis

Exploiting non-covalent interactions in selective carbohydrate synthesis

Loh CCJ (2021). Nature Reviews Chemistry   [more]
A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks

A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks

Funk J, Merino F, Schaks M, Rottner K, Raunser S, Bieling P (2021) Nature Communications [more]
Dynamic Catalytic Highly Enantioselective 1,3-Dipolar Cycloadditions

Dynamic Catalytic Highly Enantioselective 1,3-Dipolar Cycloadditions

Yildirim O, Grigalunas M, Brieger L, Strohmann C, Antonchick AP, Waldmann H (2021). Dynamic Catalytic Highly Enantioselective 1,3-Dipolar Cycloadditions. Angew Chem Int Ed Engl. [more]
Combination of pseudo-natural product design and formal natural product ring distortion yields stereochemically and biologically diverse pseudo-sesquiterpenoid alkaloids

Combination of pseudo-natural product design and formal natural product ring distortion yields stereochemically and biologically diverse pseudo-sesquiterpenoid alkaloids

Liu J, Flegel J, Otte F, Pahl A, Sievers S, Strohmann C, Waldmann H (2021). Angew Chem Int Ed Engl. [more]
Assembly principles and stoichiometry of a complete human kinetochore module

Assembly principles and stoichiometry of a complete human kinetochore module

Walstein K, Petrovic A, Pan D, Hagemeier B, Vogt D, Vetter I & Musacchio A (2021) Science Advances [more]
Growth factor–dependent ErbB vesicular dynamics couple receptor signaling to spatially and functionally distinct Erk pools

Growth factor–dependent ErbB vesicular dynamics couple receptor signaling to spatially and functionally distinct Erk pools

Brüggemann Y, Karajannis LS, Stanoev A, Stallaert W, Bastiaens PIH (2021) Science Signaling
 [more]
Natural product fragment combination to performance-diverse pseudo-natural products

Natural product fragment combination to performance-diverse pseudo-natural products

Grigalunas M, Burhop A, Zinken S, Pahl A, Gally JM, Wild N, Mantel Y, Sievers S, Foley DJ, Scheel R, Strohmann C, Antonchick AP, Waldmann H (2021) Nat Commun.
 [more]
The molecular basis for sarcomere organization in vertebrate skeletal muscle

The molecular basis for sarcomere organization in vertebrate skeletal muscle

Wang Z, Grange M, Wagner T, Khoo AL, Gautel M, Raunser S (2021) Cell  [more]
A self-organized synthetic morphogenic liposome responds with shape changes to local light cues

A self-organized synthetic morphogenic liposome responds with shape changes to local light cues

Gavriljuk K, Scocozza B, Ghasemalizadeh F, Seidel H, Nandan AP, Campos-Medina M, Schmick M, Koseska A & Bastiaens PIH (2021) Nature Communications 
[more]
Cell-Based Identification of New IDO1 Modulator Chemotypes

Cell-Based Identification of New IDO1 Modulator Chemotypes

Hennes E, Lampe P, Dötsch L, Bruning N, Pulvermacher LM, Sievers S, Ziegler S, Waldmann H (2021) Angew Chem Int Ed Engl 
 [more]
Cryo-EM resolves molecular recognition of an optojasp photoswitch bound to actin filaments in both switch states

Cryo-EM resolves molecular recognition of an optojasp photoswitch bound to actin filaments in both switch states

Pospich S, Küllmer F, Nasufovic V, Funk J, Belyy A, Bieling P, Arndt HD, Raunser S. (2021) Angew Chem Int Ed Engl  [more]
Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization

Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization

Müller F, Friese A, Pathe C, Da Silva RC, Rodriguez KB, Musacchio A, Bange T (2021) Science Advances  [more]
CDC20 assists its catalytic incorporation in the mitotic checkpoint complex

CDC20 assists its catalytic incorporation in the mitotic checkpoint complex

Piano V, Alex A, Stege P, Maffini S, Stoppiello GA, Huis In 't Veld PJ, Vetter IR, Musacchio A. (2021) Science 
 [more]
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