Publications of P. Bieling

Armstrong , M. C.; Weiß, Y. R.; Hoachlander-Hobby, L. E.; Roy, A. A.; Visco, I.; Moe, A.; Golding, A. E.; Hansen, S. D.; Bement, W. M.; Bieling, P.: The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning. The EMBO Journal (2025)

Gomez, S. M.; Visco, I.; Merino, F.; Bieling, P.; Linser, R.: Transient Structural Properties of the Rho GDP-Dissociation Inhibitor. Angewandte Chemie, International Edition in English (2024)

Rottner, K.; Bieling, P.: Illuminating cortactin structure and function at actin filament branches. Nature Structural & Molecular Biology (2024)

Oosterheert, W.; Boiero Sanders, M.; Funk, J.; Prumbaum, D.; Raunser, S.; Bieling, P.: Molecular mechanism of actin filament elongation by formins. Science (2024)

Oosterheert, W.; Blanc, F. E. C.; Roy, A.; Belyy, A.; Boiero Sanders, M.; Hofnagel, O.; Hummer, G.; Bieling, P.; Raunser, S.: Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments. Nature Structural & Molecular Biology (2023)

Boiero Sanders, M.; Oosterheert, W.; Hofnagel, O.; Bieling, P.; Raunser, S.: Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly. Nature Communications (2023)

Bieling, P.; Rottner, K.: From WRC to Arp2/3: Collective molecular mechanisms of branched actin network assembly. Current Opinion in Cell Biology (2023)

Belyy, A.; Lindemann, F.; Roderer, D.; Funk, J.; Bardiaux, B.; Protze, J.; Bieling, P.; Oschkinat, H.; Raunser, S.: Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin. Nature Communications 13 (2022)

Li, T.-D.; Bieling, P.; Weichsel, J.; Mullins, R. D.; Fletcher , D. A.: The molecular mechanism of load adaptation by branched actin networks. eLife (2022)

Funk, J.; Merino, F.; Schaks, M.; Rottner, K.; Raunser, S.; Bieling, P.: A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks. Nature Communications 12 (1), 5329, pp. 1 - 17 (2021)

Pospich, S.; Küllmer, F.; Nasufovic, V.; Funk, J.; Belyy, A.; Bieling, P.; Arndt, H.-D.; Raunser, S.: Cryo-EM resolves molecular recognition of an optojasp photoswitch bound to actin filaments in both switch states. Angewandte Chemie International Edition, pp. 1 - 7 (2021)

Pospich, S.; Küllmer, F.; Nasufovic, V.; Funk, J.; Belyy, A.; Bieling, P.; Arndt , H.-D.; Raunser, S.: Cryo‐EM resolves molecular recognition of an optojasp photoswitch bound to actin filaments in both switch states. Angewandte Chemie, pp. 1 - 7 (2021)

Funk, J.; Merino, F.; Venkova, L.; Heydenreich, L.; Kierfeld, J.; Vargas, P.; Raunser, S.; Piel, M.; Bieling, P.: Profilin and formin constitute a pacemaker system for robust actin filament growth. eLife (e50963), e50963, pp. 1 - 74 (2019)

Golding, A. E.; Visco, I.; Bieling, P.; Bement, W. M.: Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases. eLife (e50471), e50471, pp. 1 - 78 (2019)

Mullins, R. D.; Bieling, P.; Fletcher, D. A.: From solution to surface to filament: actin flux into branched networks. Biophysical Reviews 10 (6), pp. 1537 - 1551 (2018)

Merino, F.; Pospich, S.; Funk, J.; Wagner, T.; Küllmer, F.; Arndt, H.-D.; Bieling, P.; Raunser, S.: Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM. Nature Structural Molecular Biology 25 (6), pp. 528 - 537 (2018)

Schwille, P.; Spatz, J.; Landfester, K.; Bodenschatz, E.; Herminghaus, S.; Sourjik, V.; Erb, T.; Bastiaens, P. I. H.; Lipowsky, R.; Hyman, A. et al.; Dabrock, P.; Baret, J.-C.; Vidakovic-Koch, T.; Bieling, P.; Dimova, R.; Mutschler, H.; Robinson, T.; Tang, T.-Y. D.; Wegner, S.; Sundmacher, K.: MaxSynBio - Avenues towards creating cells from the bottom up. Angewandte Chemie International Edition 57 (41), pp. 13382 - 13392 (2018)

Schwille, P.; Spatz, J.; Landfester, K.; Bodenschatz, E.; Herminghaus, S.; Sourjik, V.; Erb, T.; Bastiaens, P. I. H.; Lipowsky, R.; Hyman, A. et al.; Dabrock, P.; Baret, J.-C.; Vidakovic-Koch, T.; Bieling, P.; Dimova, R.; Mutschler, H.; Robinson, T.; Tang, T.-Y. D.; Wegner, S.; Sundmacher, K.: MaxSynBio ‐ Avenues towards creating cells from the bottom up. Angewandte Chemie 130 (41), pp. 13566 - 13577 (2018)

Bieling, P.; Hansen, S. D.; Akin, O.; Li, T.-D.; Hayden, C. C.; Fletcher, D. A.; Mullins, R. D.: WH2 and proline-rich domains of WASP-family proteins collaborate to accelerate actin filament elongation. The EMBO Journal 37 (1), pp. 102 - 121 (2017)

Köster, D. V.; Husain, K.; Iljazi, E.; Bhat, A.; Bieling, P.; Mullins, R. D.; Rao, M.; Mayor, S.: Actomyosin dynamics drive local membrane component organization in an in vitro active composite layer. Proceedings of the National Academy of Sciences of the United States of America 113 (12), pp. E1645 - E1654 (2016)