Publications of Kirill Alexandrov

Guo, Z.; Wu, Y.-W.; Das, D.; Delon, C.; Cramer, J.; Yu, S.; Thuns, S.; Lupilova, N.; Waldmann, H.; Brunsveld, L. et al.; Goody, R. S.; Alexandrov, K.; Blankenfeldt, W.: Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. The EMBO Journal 27 (18), 1, pp. 2444 - 2456 (2008)

Wong, E.; Okhonin, V.; Berezovski, M. V.; Nozaki, T.; Waldmann, H.; Alexandrov, K.; Krylov, S. N.: "Inject-Mix-React-Separate-and-Quantitate" (IMReSQ) Method for Screening Enzyme Inhibitors. Journal of the American Chemical Society 130 (36), 1, pp. 11862 - 11863 (2008)

Guo, Z.; Wu, Y.-W.; Tan, K.-T.; Bon, R. S.; Guiu Rozas, E.; Delon, C.; Nguyen, U. T.; Wetzel, S.; Arndt, S.; Goody, R. S. et al.; Blankenfeldt, W.; Alexandrov, K.; Waldmann, H.: Development of Selective RabGGTase Inhibitors and Crystal Structure of a RabGGTase-Inhibitor Complex. Angewandte Chemie International Edition 47 (20), 1, pp. 3747 - 3750 (2008)

Guo, Z.; Wu, Y.-W.; Tan, K.-T.; Bon, R. S.; Guiu-Rozas, E.; Delon, C.; Nguyen, U. T.; Wetzel, S.; Arndt, S.; Goody, R. S. et al.; Blankenfeldt, W.; Alexandrov, K.; Waldmann, H.: Development of Selective RabGGTase Inhibitors and Crystal Structure of a RabGGTase-Inhibitor Complex. Angewandte Chemie 120 (20), 1, pp. 3807 - 3810 (2008)

Wu, Y.-W.; Alexandrov, K.; Brunsveld, L.: Synthesis of a fluorescent analogue of geranylgeranyl pyrophosphate and its use in a high-throughput fluorometric assay for Rab geranylgeranyltransferase. Nature Protocols 2 (11), 1, pp. 2704 - 2711 (2007)

Wu, Y.-W.; Tan, K.-T.; Waldmann, H.; Goody, R. S.; Alexandrov, K.: Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators. Proceedings of the National Academy of Sciences of the United States of America 104 (30), 1, pp. 12294 - 12299 (2007)

Mureev, S.; Kushnir, S.; Kolesnikov, A. A.; Breitling, R.; Alexandrov, K.: Construction and analysis of Leishmania tarentolae transgenic strains free of selection markers. Molecular & Biochemical Parasitology 155 (2), 1, pp. 71 - 83 (2007)

Nguyen, U. T. T.; Cramer, J.; Gomis, J.; Reents, R.; Gutierrez-Rodriguez, M.; Goody, R. S.; Alexandrov, K.; Waldmann, H.: Exploiting the Substrate Tolerance of Farnesyltransferase for Site-Selective Protein Derivatization. ChemBioChem 8 (4), 1, pp. 408 - 423 (2007)

Wu, Y.-W.; Waldmann, H.; Reents, R.; Ebetino, F. H.; Goody, R. S.; Alexandrov, K.: A Protein Fluorescence Amplifier: Continuous Fluorometric Assay for Rab Geranylgeranyltransferase. ChemBioChem 7 (12), 1, pp. 1859 - 1861 (2006)

Marsac, Y.; Cramer, J.; Olschewski, D.; Alexandrov, K.; Becker, C. F. W.: Site-Specific Attachment of Polyethylene Glycol-like Oligomers to Proteins and Peptides. Bioconjugate Chemistry 17 (6), 1, pp. 1492 - 1498 (2006)

Brunsveld, L.; Kuhlmann, J.; Alexandrov, K.; Wittinghofer, A.; Goody, R. S.; Waldmann, H.: Lipidated Ras and Rab Peptides and Proteins - Synthesis, Structure, and Function. Angewandte Chemie International Edition 45 (40), 1, pp. 6622 - 6646 (2006)

Brunsveld, L.; Kuhlmann, J.; Alexandrov, K.; Wittinghofer, A.; Goody, R. S.; Waldmann, H.: Lipidierte Ras- und Rab-Peptide und -Proteine: Synthese, Struktur und Funktion. Angewandte Chemie 118 (40), 1, pp. 6774 - 6798 (2006)

Watzke, A.; Gutierrez-Rodriguez, M.; Köhn, M.; Wacker, R.; Schroeder, H.; Breinbauer, R.; Kuhlmann, J.; Alexandrov, K.; Niemeyer, C. M.; Goody, R. S. et al.; Waldmann, H.: A generic building block for C- and N-terminal protein-labeling and protein-immobilization. Bioorganic & Medicinal Chemistry 14 (18), 1, pp. 6288 - 6306 (2006)

Niculae, A.; Bayer, P.; Cirstea, I.; Bergbrede, T.; Pietrucha, R.; Gruen, M.; Breitling, R.; Alexandrov, K.: Isotopic labeling of recombinant proteins expressed in the protozoan host Leishmania tarentolae. Protein Expression and Purification 48 (2), 1, pp. 167 - 172 (2006)

de Araújo, A. D.; Palomo, J. M.; Cramer, J.; Seitz, O.; Alexandrov, K.; Waldmann, H.: Diels-Alder Ligation of Peptides and Proteins. Chemistry - A European Journal 12 (23), 1, pp. 6095 - 6109 (2006)

Seibert, S. F.; Eguereva, E.; Krick, A.; Kehraus, S.; Voloshina, E.; Raabe, G.; Fleischhauer, J.; Leistner, E.; Wiese, M.; Prinz, H. et al.; Alexandrov, K.; Janning, P.; Waldmann, H.; König, G. M.: Polyketides from the marine-derived fungus Ascochyta salicorniae and their potential to inhibit protein phosphatases. Organic & Biomolecular Chemistry 4 (11), 1, pp. 2233 - 2240 (2006)

Kushnir, S.; Marsac, Y.; Breitling, R.; Granovsky, I.; Brok-Volchanskaya, V.; Goody, R. S.; Becker, C. F. W.; Alexandrov, K.: Rapid Production of Functionalized Recombinant Proteins: Marrying Ligation Independent Cloning and in Vitro Protein Ligation. Bioconjugate Chemistry 17 (3), 1, pp. 610 - 617 (2006)

Lukes, J.; Paris, Z.; Regmi, S.; Breitling, R.; Mureev, S.; Kushnir, S.; Pyatkov, K.; Jirku, M.; Alexandrov, K. A.: Translational initiation in Leishmania tarentolae and Phytomonas serpens (Kinetoplastida) is strongly influenced by pre-ATG triplet and its 5′ sequence context. Molecular and Biochemical Parasitology 148 (2), 1, pp. 125 - 132 (2006)

Becker, C. F. W.; Seidel, R.; Jahnz, M.; Bacia, K.; Niederhausen, T.; Alexandrov, K.; Schwille, P.; Goody, R. S.; Engelhard, M.: C-Terminal Fluorescence Labeling of Proteins for Interaction Studies on the Single-Molecule Level. ChemBioChem 7 (6), 1, pp. 891 - 895 (2006)

Itzen, A.; Pylypenko, O.; Goody, R. S.; Alexandrov, K.; Rak, A.: Nucleotide exchange via local protein unfolding - structure of Rab8 in complex with MSS4. The EMBO Journal 25 (7), 1, pp. 1445 - 1455 (2006)