Publications of Philippe I. H. Bastiaens

Martín-Gago, P.; Fansa, E. K.; Klein, C.; Murarka, S.; Janning, P.; Schürmann, M.; Metz, M.; Ismail, S.; Schultz-Fademrecht, C.; Baumann, M. et al.; Bastiaens, P. I. H.; Wittinghofer, A.; Waldmann, H.: A PDE6d-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2. Angewandte Chemie 129 (9), pp. 2463 - 2468 (2017)

Masip, M.; Hübinger, J.; Christmann, J.; Sabet, O.; Wehner, F.; Konitsiotis, A.; Fuhr, G. R.; Bastiaens, P. I. H.: Reversible cryo-arrest for imaging molecules in living cells at high spatial resolution. Nature methods 13 (8), pp. 665 - 672 (2016)

Papke, B.; Murarka, S.; Vogel, H. A.; Martín-Gago, P.; Kovacevic, M.; Truxius, D.; Fansa, E. K.; Ismail, S.; Zimmermann, G.; Heinelt, K. et al.; Schultz-Fademrecht, C.; Al Saabi, A.; Baumann, M.; Nussbaumer, P.; Wittinghofer, A.; Waldmann, H.; Bastiaens, P. I. H.: Identification of pyrazolopyridazinones as PDEδ inhibitors. Nature Communications 7, 11360, pp. 1 - 9 (2016)

Christmann, J.; Azer, L.; Dörr, D.; Fuhr, G. R.; Bastiaens, P. I. H.; Wehner, F.: Adaptive responses of cell hydration to a low temperature arrest. The Journal of Physiology - London 594 (6), pp. 1663 - 1676 (2016)

Baumdick, M.; Brüggemann, Y.; Schmick, M.; Xouri, G.; Sabet, O.; Davis, L.; Chin, J. W.; Bastiaens, P. I. H.: EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling. eLife, pp. e12223:1 - e12223:71 (2015)

Ibach, J.; Radon, Y.; Gelleri, M.; Sonntag, M. H.; Brunsveld, L.; Bastiaens, P. I. H.; Verveer, P. J.: Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits. PLoS One 10 (11), pp. e0143162:1 - e0143162:22 (2015)

Hübinger, J.; Han, H.; Hofnagel, O.; Vetter, I. R.; Bastiaens, P. I. H.; Grabenbauer, M.: Direct Measurement of Water States in Cryopreserved Cells Reveals Tolerance toward Ice Crystallization. Biophysical Journal 110 (4), pp. 840 - 849 (2015)

Sabet, O.; Stockert, R.; Xouri, G.; Brüggemann, Y.; Stanoev, A.; Bastiaens, P. I. H.: Ubiquitination switches EphA2 vesicular traffic from a continuous safeguard to a finite signalling mode. Nature Communications 6, 8047, pp. 1 - 13 (2015)

Nakhaei-Rad, S.; Nakhaeizadeh, H.; Kordes, C.; Cirstea, I. C.; Schmick, M.; Dvorsky, R.; Bastiaens, P. I. H.; Häussinger, D.; Ahmadian, M. R.: The function of embryonic stem cell-expressed Ras (E-Ras), a unique Ras family member, correlates with its additional motifs and its structural properties. The Journal of Biological Chemistry 290 (25), pp. 15892 - 15903 (2015)

Berg, V.; Rusch, M.; Vartak, N.; Jüngst, C.; Schauss, A.; Waldmann, H.; Hedberg, C.; Pallasch, C. P.; Bastiaens, P. I. H.; Hallek, M. et al.; Wendtner, C.-M.; Frenzel, L. P.: miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in chronic lymphocytic leukemia. Blood 125 (19), pp. 2948 - 2957 (2015)

Bastiaens, P. I. H.; Birtwistle, M. R.; Blüthgen, N.; Bruggeman, F. J.; Cho, K.-H.; Cosentino, C.; de la Fuente, A.; Hoek, J. B.; Kiyatkin, A.; Klamt, S. et al.; Kolch, W.; Legewie, S.; Mendes, P.; Naka, T.; Santra, T.; Sontag, E.; Westerhoff, H. V.; Kholodenko, B. N.: Silence on the relevant literature and errors in implementation. Nature biotechnology 33 (4), pp. 336 - 339 (2015)

Schmick, M.; Krämer, A.; Bastiaens, P. I. H.: Ras moves to stay in place. Trends in Cell Biology 25 (4), pp. 190 - 197 (2015)

Arrabito, G.; Schroeder, H.; Schröder, K.; Filips, C.; Marggraf, U.; Dopp, C.; Venkatachalapathy, M.; Dehmelt, L.; Bastiaens, P. I. H.; Neyer, A. et al.; Niemeyer, C. M.: Configurable Low-Cost Plotter Device for Fabrication of Multi-Color Sub-Cellular Scale Microarrays. Small 10 (14), pp. 2870 - 2876 (2014)

Schmick, M.; Vartak, N.; Papke, B.; Kovacevic, M.; Truxius, D.; Rossmannek, L.; Bastiaens, P. I. H.: KRas Localizes to the Plasma Membrane by Spatial Cycles of Solubilization, Trapping and Vesicular Transport. Cell 157 (2), pp. 459 - 471 (2014)

Schmick, M.; Bastiaens, P. I. H.: The Interdependence of Membrane Shape and Cellular Signal Processing. Cell 156 (6), pp. 1132 - 1138 (2014)

Schaupp, A.; Sabet, O.; Dudanova, I.; Ponserre, M.; Bastiaens, P. I. H.; Klein, R.: The composition of EphB2 clusters determines the strength in the cellular repulsion response. The Journal of Cell Biology: JCB 204 (3), pp. 409 - 422 (2014)

Vartak, N.; Papke, B.; Grecco, H. E.; Rossmannek, L.; Waldmann, H.; Hedberg, C.; Bastiaens, P. I. H.: The Autodepalmitoylating Activity of APT Maintains the Spatial Organization of Palmitoylated Membrane Proteins. Biophysical Journal 106 (1), pp. 93 - 105 (2014)

Roda-Navarro, P.; Bastiaens, P. I. H.: Dynamic recruitment of protein tyrosine phosphatase PTPD1 to EGF stimulation sites potentiates EGFR activation. PLoS One 9 (7), e103203, pp. 1 - 12 (2014)

Arrabito, G.; Reisewitz, S.; Dehmelt, L.; Bastiaens, P. I. H.; Pignataro, B.; Schroeder, H.; Niemeyer, C. M.: Biochips for Cell Biology by Combined Dip-Pen Nanolithography and DNA-Directed Protein Immobilization. Small 9 (24), pp. 4243 - 4249 (2013)

Symeonidou, I.-E.; Kotsantis, P.; Roukos, V.; Rapsomaniki, M.-A.; Grecco, H. E.; Bastiaens, P.; Taraviras, S.; Lygerou, Z.: Multi-step loading of human Mini Chromosome Maintenance proteins in live human cells. The Journal of Biological Chemistry, Epub ahead of print; no final pagination, pp. 1 - 26 (2013)