Publications of Gunther Zimmermann

Küchler, P.; Zimmermann, G.; Winzker, M.; Janning, P.; Waldmann, H.; Ziegler, S.: Identification of novel PDEd interacting proteins. Bioorganic & Medicinal Chemistry 26 (8), pp. 1426 - 1434 (2017)

Papke, B.; Murarka, S.; Vogel, H. A.; Martín-Gago, P.; Kovacevic, M.; Truxius, D.; Fansa, E. K.; Ismail, S.; Zimmermann, G.; Heinelt, K. et al.; Schultz-Fademrecht, C.; Al Saabi, A.; Baumann, M.; Nussbaumer, P.; Wittinghofer, A.; Waldmann, H.; Bastiaens, P. I. H.: Identification of pyrazolopyridazinones as PDEδ inhibitors. Nature Communications 7, 11360, pp. 1 - 9 (2016)

Zimmermann, G.; Schultz-Fademrecht, C.; Küchler, P.; Murarka, S.; Ismail, S.; Triola, G.; Nussbaumer, P.; Wittinghofer, A.; Waldmann, H.: Structure Guided Design and Kinetic Analysis of Highly Potent Benzimidazole Inhibitors Targeting the PDEδ Prenyl Binding Site. Journal of Medicinal Chemistry 57 (12), pp. 5435 - 5448 (2014)

Spiegel, J.; Cromm, P. M.; Zimmermann, G.; Grossmann, T.; Waldmann, H.: Small-molecule modulation of Ras signaling. Nature Chemical Biology 10 (8), pp. 613 - 622 (2014)

Zimmermann, G.; Papke, B.; Ismail, S.; Vartak, N.; Chandra, A.; Hoffmann, M.; Hahn, S. A.; Triola, G.; Wittinghofer, A.; Bastiaens, P. I. H. et al.; Waldmann, H.: Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature 497 (7451), 1, pp. 638 - 642 (2013)