Publications of Andrea Musacchio

Walstein, K.; Petrovic, A.; Pan, D.; Hagemeier, B.; Vogt, D.; Vetter, I. R.; Musacchio, A.: Assembly principles and stoichiometry of a complete human kinetochore module. Science Advances 7 (27), eabg1037, pp. 1 - 22 (2021)

Müller, F.; Friese, A.; Pathe, C.; Cardoso da Silva, R.; Bravo Rodriguez, K.; Musacchio, A.; Bange, T.: Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization. Science Advances 7 (3), eabc8590, pp. 1 - 13 (2021)

Piano, V.; Alex, A.; Stege, P.; Maffini, S.; Stoppiello, G. A.; Huis in´t Veld, P. J.; Vetter, I. R.; Musacchio, A.: CDC20 assists its catalytic incorporation in the mitotic checkpoint complex. Science 371 (6524), pp. 67 - 71 (2021)

Singh, P.; Pesenti, M.; Maffini, S.; Carmignani, S.; Hedtfeld, M.; Petrovic, A.; Srinivasamani, A.; Bange, T.; Musacchio, A.: BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis. Molecular Cell 81 (1), pp. 67 - 87 (2020)

Kong, M.; Cutts, E. E.; Pan, D.; Beuron, F.; Kaliyappan, T.; Xue, C.; Morris, E. P.; Musacchio, A.; Vannini, A.; Greene, E. C.: Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA. Molecular Cell 79 (1), pp. 99 - 114 (2020)

Allan, L. A.; Camacho Reis, M.; Ciossani, G.; Huis in´t Veld, P. J.; Wohlgemuth, S.; Kops, G. J.; Musacchio, A.; Saurin, A. T.: Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpoint. The EMBO Journal 39 (12), e103180, pp. 1 - 16 (2020)

Huis in´t Veld, P. J.; Volkov, V. A.; Stender, I. D.; Musacchio, A.; Dogterom, M.: Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling. eLife 8:e49539, e49539, pp. 1 - 29 (2019)

Pan, D.; Walstein, K.; Take, A.; Bier, D.; Kaiser, N.; Musacchio, A.: Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing. Nature Communications 10 (1), 4046, pp. 1 - 18 (2019)

Alex, A.; Piano, V.; Polley, S.; Stuiver, M.; Voss, S.; Ciossani, G.; Overlack, K.; Voss, B.; Wohlgemuth, S.; Petrovic, A. et al.; Wu, Y.-W.; Selenko, P.; Musacchio, A.; Maffini, S.: Electroporated recombinant proteins as tools for in vivo functional complementation, imaging, and chemical biology. eLife 8, e48287, pp. 1 - 50 (2019)

Pesenti, M.; Prumbaum, D.; Auckland, P.; Smith, C.; Faesen, A. C.; Petrovic, A.; Erent, M.; Maffini, S.; Pentakota, S.; Weir, J. R. et al.; Lin, Y.-C.; Raunser, S.; McAinsh, A. D.; Musacchio, A.: Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80. Molecular Cell 71 (6), e10, pp. 923 - 939 (2018)

Pan, D.; Brockmeyer, A.; Müller, F.; Musacchio, A.; Bange, T.: Simplified Protocol for Cross-linking Mass Spectrometry Using the MS-Cleavable Cross-linker DSBU with Efficient Cross-link Identification. Analytical Chemistry 90 (18), pp. 10990 - 10999 (2018)

Sacristan, C.; Ahmad, M. U. D.; Keller, J.; Fermie, J.; Groenewold, V.; Tromer, E.; Fish, A.; Melero, R.; Carazo , J. M.; Klumperman, J. et al.; Musacchio, A.; Perrakis, A.; Kops, G. J.: Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis. Nature Cell Biology 20 (7), pp. 800 - 810 (2018)

Ciossani, G.; Overlack, K.; Petrovic, A.; Huis in´t Veld, P. J.; Koerner, C.; Wohlgemuth, S.; Maffini, S.; Musacchio, A.: The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases. The Journal of Biological Chemistry 293 (26), pp. 10084 - 10101 (2018)

Volkov, V. A.; Huis in´t Veld, P. J.; Dogterom, M.; Musacchio, A.: Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces. eLife, e36764, pp. e36764:1 - e36764:47 (2018)

Weith, M.; Seiler, J.; van den Boom, J.; Kracht, M.; Hülsmann, J.; Primorac, I.; del Pino Garcia, J.; Kaschani, F.; Kaiser, M.; Musacchio, A. et al.; Bollen, M.; Meyer, H.: Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation. Molecular Cell 72, pp. 1 - 19 (2018)

Pentakota, S.; Zhou, K.; Smith, C.; Maffini, S.; Petrovic, A.; Morgan, G. P.; Weir, J. R.; Vetter, I. R.; Musacchio, A.; Luger, K.: Decoding the centromeric nucleosome through CENP-N. eLife, 6:e33442, pp. e33442:1 - e33442:25 (2017)

Overlack, K.; Bange, T.; Weissmann, F.; Faesen, A. C.; Maffini, S.; Primorac, I.; Müller, F.; Peters, J.-M.; Musacchio, A.: BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling. Current Biology 27 (19), pp. 2915 - 2927 (2017)

Vader, G.; Musacchio, A.: The greatest kinetochore show on earth. EMBO Reports 18 (9), e201744541, pp. 1473 - 1475 (2017)

Mosalaganti, S.; Keller, J.; Altenfeld, A.; Winzker, M.; Rombaut, P.; Saur, M.; Petrovic, A.; Wehenkel, A.; Wohlgemuth, S.; Müller, F. et al.; Maffini, S.; Bange, T.; Herzog, F.; Waldmann, H.; Raunser, S.; Musacchio, A.: Structure of the RZZ complex and molecular basis of its interaction with Spindly. The Journal of Cell Biology: JCB 216 (4), pp. 961 - 981 (2017)

Musacchio, A.; Desai, A.: A Molecular View of Kinetochore Assembly and Function. Biology 6 (1), pp. 1 - 47 (2017)