Publications of Roger S. Goody

Constantinescu, A.-T.; Rak, A.; Alexandrov, K.; Esters, H.; Goody, R. S.; Scheidig, A. J.: Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases. Structure 10 (4), 1, pp. 569 - 579 (2002)

Thomä, N. H.; Iakovenko, A.; Goody, R. S.; Alexandrov, K.: Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1. Journal of Biological Chemistry 276 (52), 1, pp. 48637 - 48643 (2001)

Thomä, N. H.; Niculae, A.; Goody, R. S.; Alexandrov, K.: Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate. Journal of Biological Chemistry 276 (52), 1, pp. 48631 - 48636 (2001)

Rak, A.; Reents, R.; Pylypenko, O.; Niculae, A.; Sidorovitch, V.; Thomä, N. H.; Waldmann, H.; Schlichting, I.; Goody, R. S.; Alexandrov, K.: Crystallization and preliminary X-ray diffraction analysis of the Rab escort protein-1 in complex with Rab geranylgeranyltransferase. Journal of Structural Biology 136 (2), 1, pp. 158 - 161 (2001)

Thomä, N. H.; Iakovenko, A.; Kalinin, A.; Waldmann, H.; Goody, R. S.; Alexandrov, K.: Allosteric regulation of substrate binding and product release in geranylgeranyltransferase Type II. Biochemistry 40, pp. 268 - 274 (2001)

Thoma, N.; Iakovenko, A.; Owen, D.; Scheidig, A. J.; Waldmann, H.; Goody, R. S.; Alexandrov, K. A.: Phosphoisoprenoid binding specificity of geranylgeranyltransferase type II. BIOCHEMISTRY 39 (39), pp. 12043 - 12052 (2000)

Alexandrov, K. A.; Simon, I.; Yurchenko, V.; Iakovenko, A.; Rostkova, E.; Scheidig, A. J.; Goody, R. S.: Characterization of the ternary complex between Rab7, REP-1 and Rab geranylgeranyl transferase. European Journal of Biochemistry 265, pp. 160 - 170 (1999)

Owen, D.; Alexandrov, K. A.; Rostkova, E.; Scheidig, A. J.; Goody, R. S.; Waldmann, H.: Chemo-enzymatic synthesis of fluorescent Rab 7 proteins: Tools to study vesicular trafficking in cells. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 38 (4), pp. 509 - 512 (1999)

Alexandrov, K. A.; Simon, I.; Iakovenko, A.; Holz, B.; Goody, R. S.; Scheidig, A. J.: Moderate discrimination of REP-1 between Rab7-GDP and Rab7-GTP arises from a difference of an order of magnitude in dissociation rates. FEBS Letters 425 (3), pp. 460 - 464 (1998)

Ahmadian, M. R.; Hoffmann, U.; Goody, R. S.; Wittinghofer, A.: Individual rate constants for the interaction of Ras proteins with GTPase-activating proteins determined by fluorescence spectroscopy. Biochemistry 36 (15), 1, pp. 4535 - 4541 (1997)

Ahmadian, M. R.; Hoffmann, U.; Goody, R. S.; Wittinghofer, A.: Individual rate constants for the interaction of Ras proteins with GTPase-activating proteins determined by fluorescence spectroscopy. Biochemistry 36 (15), pp. 4535 - 4541 (1997)

Haller, M.; Hoffmann, U.; Schanding, T.; Goody, R. S.; Vogel, P. D.: Nucleotide hydrolysis-dependent conformational changes in p21^ras as studied using ESR spectroscopy. The Journal of Biological Chemistry 272, pp. 30103 - 30107 (1997)

Krebs, R.; Immendörfer, U.; Thrall, S. H.; Wöhrl, B. M.; Goody, R. S.: Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC. Biochemistry 36 (33), pp. 10292 - 10300 (1997)

Lavie, A.; Schlichting, I.; Vetter, I. R.; Konrads, M.; Reinstein, J.; Goody, R. S.: The bottleneck in AZT activation. Nature Medicine 3, pp. 922 - 924 (1997)

Lavie, A.; Vetter, I. R.; Konrad, M.; Goody, R. S.; Reinstein, J.; Schlichting, I.: Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation. Nature structural biology 4, pp. 601 - 604 (1997)

Metzger, A. U.; Bayer, P.; Willbold, D.; Hoffmann, S.; Frank, R. W.; Goody, R. S.; Rösch, P.: The interaction of HIV-1 Tat(32-72) with its target RNA: A fluorescence and nuclear magnetic resonance study. Biochemical and Biophysical Research Communications 241 (1), pp. 31 - 36 (1997)

Moser, C.; Mol, O.; Goody, R. S.; Sinning, I.: The signal recognition particle receptor of Escherichia coli (FtsY) has a nucleotide exchange factor built into the GTPase domain. Proceedings of the National Academy of Sciences of the United States of America 94 (21), pp. 11339 - 11344 (1997)

Packschies, L.; Theyssen, H.; Buchberger, A.; Bukau, B.; Goody, R. S.; Reinstein, J.: GrpE accelerates nucleotide exchange of the molecular chaperone DnaK with an associative displacement mechanism. Biochemistry 36 (12), pp. 3417 - 3422 (1997)

Pelicano, H.; Maury, G.; Elalaoui, A.; Shafiee, M.; Imbach, J.-L.; Goody, R. S.; Divita, G.: Study of the substrate-binding properties of bovine liver adenosine kinase and inhibition by fluorescent nucleoside analogues. European Journal of Biochemistry 248 (3), pp. 930 - 937 (1997)

Arts, E. J.; Stetor, S. R.; Li, X.; Rausch, J. W.; Howard, K. J.; Ehresmann, B.; North, T. W.; Wöhrl, B. M.; Goody, R. ..; Wainberg, M. A. et al.; Le Grice, S. F. J.: Initiation of (-) strand DNA synthesis from tRNA₃^Lys on lentiviral RNAs: Implications of specific HIV-1 RNA-tRNA₃^Lys interactions inhibiting primer utilization by retroviral reverse transcriptases. Proceedings of the National Academy of Sciences of the United States of America 93 (19), 1, pp. 10063 - 10068 (1996)