Key Publications 2020

Optogenetic Tuning Reveals Rho Amplification-Dependent Dynamics of a Cell Contraction Signal Network

Optogenetic Tuning Reveals Rho Amplification-Dependent Dynamics of a Cell Contraction Signal Network

Kamps, D, Koch J, Juma VO, Campillo-Funollet E, Graessl M, Banerjee S, Mazel T, Chen X, Wu YW, Portet S, Madzvamuse A, Nalbant P, Dehmelt L (2020) Cell Reports

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BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis

BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis

Singh P, Pesenti ME, Maffini S, Carmignani S, Hedtfeld M, Petrovic A, Srinivasamani A, Bange T, Musacchio A (2020) Mol Cell 
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<p class="p1">Structural basis of TRPC4 regulation by calmodulin and pharmacological agents</p>

Structural basis of TRPC4 regulation by calmodulin and pharmacological agents

Vinayagam D, Quentin D, Yu-Strzelczyk J, Sitsel O, Merino F, Stabrin M, Hofnagel O, Yu M, Ledeboer MW, Nagel G, Malojcic G, Raunser S (2020) eLife

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Design, synthesis and biological evaluation of chemically and biologically diverse pyrroquinoline pseudo natural products

Design, synthesis and biological evaluation of chemically and biologically diverse pyrroquinoline pseudo natural products

Liu J, Cremosnik GS, Otte F, Pahl A, Sievers S, Strohmann C, Waldmann H  (2020) Angew Chem Int Ed Engl

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<p class="p1">TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM</p>

TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM

Stabrin M, Schoenfeld F, Wagner T, Pospich S, Gatsogiannis C, Raunser S (2020) Nat Commun

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A protein tertiary structure mimetic modulator of the Hippo signalling pathway

A protein tertiary structure mimetic modulator of the Hippo signalling pathway

Adihou H, Gopalakrishnan R, Förster T, Guéret SM, Gasper R, Geschwindner S, Carrillo García C, Karatas H, Pobbati AV, Vazquez-Chantada M, Davey P, Wassvik CM, Pang JKS, Soh BS, Hong W, Chiarparin E, Schade D, Plowright AT, Valeur E, Lemurell M, Grossmann TN, Waldmann H. (2020) Nat Commun

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Structure based design of bicyclic peptide inhibitors of RbAp48

Structure based design of bicyclic peptide inhibitors of RbAp48

Adihou H, 't Hart P, Hommen P, Noisier A, Krzyzanowski A, Schüler D, Porfetye AT, Akbarzadeh M, Vetter IR, Waldmann H (2020) Angew Chem Int Ed Engl

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Processing Temporal Growth Factor Patterns by an Epidermal Growth Factor Receptor Network Dynamically Established in Space

Processing Temporal Growth Factor Patterns by an Epidermal Growth Factor Receptor Network Dynamically Established in Space

Koseska A, Bastiaens PIH (2020) Annu Rev Cell Biol

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<p>A robust and tunable halogen bond organocatalyzed 2-deoxyglycosylation involving quantum tunneling</p>

A robust and tunable halogen bond organocatalyzed 2-deoxyglycosylation involving quantum tunneling

Xu C, Bhaskara Rao VU, Weigen J, Loh CCJ.  (2020) Nat Commun

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Homeostatic Control of Meiotic Prophase Checkpoint Function by Pch2 and Hop1

Homeostatic Control of Meiotic Prophase Checkpoint Function by Pch2 and Hop1

Raina VB, Vader G (2020) Current Biology

doi: https://doi.org/10.1016/j.cub.2020.08.064. [mehr]
The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members

The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members

Rai A, Bleimling N, Vetter IR, Goody RS (2020) Nat Commun

doi: 10.1038/s41467-020-17792-3. [mehr]
<p>Glycan-dependent Cell Adhesion Mechanism of Tc Toxins</p>

Glycan-dependent Cell Adhesion Mechanism of Tc Toxins

Roderer D, Bröcker F, Sitsel O, Kaplonek P, Leidreiter F, Seeberger PH, Raunser S (2020) Nat Commun

doi: 10.1038/s41467-020-16536-7. [mehr]
Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA

Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA

Kong M, Cutts EE, Pan D, Beuron F, Kaliyappan T, Xue C, Morris EP, Musacchio A, Vannini A, Greene EC. (2020) Mol Cell

doi: 10.1016/j.molcel.2020.04.026. [mehr]
Cyclin B1 Scaffolds MAD1 at the Kinetochore Corona to Activate the Mitotic Checkpoint

Cyclin B1 Scaffolds MAD1 at the Kinetochore Corona to Activate the Mitotic Checkpoint

Allan LA, Camacho Reis M, Ciossani G, Huis In 't Veld PJ, Wohlgemuth S, Kops GJ, Musacchio A, Saurin AT. (2020) EMBO J.

doi: 10.15252/embj.2019103180. [mehr]
Evolved, Selective Erasers of Distinct Lysine Acylations

Evolved, Selective Erasers of Distinct Lysine Acylations

Spinck M, Neumann-Staubitz P, Ecke M, Gasper R, Neumann H (2020) Angew Chem Int Ed Engl.

doi: 10.1002/anie.202002899. [mehr]
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