MPI of Molecular Physiology Research Key Publications keypublications2020 Selected Publications 2020 Optogenetic Tuning Reveals Rho Amplification-Dependent Dynamics of a Cell Contraction Signal Network Kamps, D, Koch J, Juma VO, Campillo-Funollet E, Graessl M, Banerjee S, Mazel T, Chen X, Wu YW, Portet S, Madzvamuse A, Nalbant P, Dehmelt L (2020) Cell Reports Source [more] BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis Singh P, Pesenti ME, Maffini S, Carmignani S, Hedtfeld M, Petrovic A, Srinivasamani A, Bange T, Musacchio A (2020) Mol Cell Source [more] Structural basis of TRPC4 regulation by calmodulin and pharmacological agents Vinayagam D, Quentin D, Yu-Strzelczyk J, Sitsel O, Merino F, Stabrin M, Hofnagel O, Yu M, Ledeboer MW, Nagel G, Malojcic G, Raunser S (2020) eLife Source [more] Design, synthesis and biological evaluation of chemically and biologically diverse pyrroquinoline pseudo natural products Liu J, Cremosnik GS, Otte F, Pahl A, Sievers S, Strohmann C, Waldmann H (2020) Angew Chem Int Ed Engl Source [more] TranSPHIRE: automated and feedback-optimized on-the-fly processing for cryo-EM Stabrin M, Schoenfeld F, Wagner T, Pospich S, Gatsogiannis C, Raunser S (2020) Nat Commun Source [more] A protein tertiary structure mimetic modulator of the Hippo signalling pathway Adihou H, Gopalakrishnan R, Förster T, Guéret SM, Gasper R, Geschwindner S, Carrillo García C, Karatas H, Pobbati AV, Vazquez-Chantada M, Davey P, Wassvik CM, Pang JKS, Soh BS, Hong W, Chiarparin E, Schade D, Plowright AT, Valeur E, Lemurell M, Grossmann TN, Waldmann H. (2020) Nat Commun Source [more] Structure based design of bicyclic peptide inhibitors of RbAp48 Adihou H, 't Hart P, Hommen P, Noisier A, Krzyzanowski A, Schüler D, Porfetye AT, Akbarzadeh M, Vetter IR, Waldmann H (2020) Angew Chem Int Ed Engl Source [more] Processing Temporal Growth Factor Patterns by an Epidermal Growth Factor Receptor Network Dynamically Established in Space Koseska A, Bastiaens PIH (2020) Annu Rev Cell Biol Quelle [more] A robust and tunable halogen bond organocatalyzed 2-deoxyglycosylation involving quantum tunneling Xu C, Bhaskara Rao VU, Weigen J, Loh CCJ. (2020) Nat Commun Source [more] Homeostatic Control of Meiotic Prophase Checkpoint Function by Pch2 and Hop1 Raina VB, Vader G (2020) Current Biology doi: https://doi.org/10.1016/j.cub.2020.08.064. [more] The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members Rai A, Bleimling N, Vetter IR, Goody RS (2020) Nat Commun doi: 10.1038/s41467-020-17792-3. [more] Glycan-dependent Cell Adhesion Mechanism of Tc Toxins Roderer D, Bröcker F, Sitsel O, Kaplonek P, Leidreiter F, Seeberger PH, Raunser S (2020) Nat Commun doi: 10.1038/s41467-020-16536-7. [more] Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA Kong M, Cutts EE, Pan D, Beuron F, Kaliyappan T, Xue C, Morris EP, Musacchio A, Vannini A, Greene EC. (2020) Mol Cell doi: 10.1016/j.molcel.2020.04.026. [more] Cyclin B1 Scaffolds MAD1 at the Kinetochore Corona to Activate the Mitotic Checkpoint Allan LA, Camacho Reis M, Ciossani G, Huis In 't Veld PJ, Wohlgemuth S, Kops GJ, Musacchio A, Saurin AT. (2020) EMBO J. doi: 10.15252/embj.2019103180. [more] Evolved, Selective Erasers of Distinct Lysine Acylations Spinck M, Neumann-Staubitz P, Ecke M, Gasper R, Neumann H (2020) Angew Chem Int Ed Engl. doi: 10.1002/anie.202002899. [more]