Publications of Slava Ziegler

Kapoor, S.; Waldmann, H.; Ziegler, S.: Novel approaches to map small molecule–target interactions. Bioorganic & Medicinal Chemistry, pp. 1 - 14 (2016)

Sellstedt, M.; Schwalfenberg, M.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Trienamine catalyzed asymmetric synthesis and biological investigation of a cytochalasin B-inspired compound collection. Organic & Biomolecular Chemistry 14 (1), pp. 50 - 54 (2015)

Roos, J.; Grösch, S.; Werz, O.; Schröder, P.; Ziegler, S.; Fulda, S.; Paulus, P.; Urbschat, A.; Kühn, B.; Maucher, I. et al.; Fettel, J.; Vorup-Jensen, T.; Piesche, M.; Matrone, C.; Steinhilber, D.; Parnham, M. J.; Maier, T. J.: Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells? Pharmacology & Therapeutics 157, pp. 43 - 64 (2015)

Schröder, P.; Förster, T.; Kleine, S.; Becker, C.; Richters, A.; Ziegler, S.; Rauh, D.; Kumar, K.; Waldmann, H.: Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4. Angewandte Chemie International Edition 54 (42), pp. 12398 - 12403 (2015)

Schröder, P.; Förster, T.; Kleine, S.; Becker, C.; Richters, A.; Ziegler, S.; Rauh, D.; Kumar, K.; Waldmann, H.: Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4. Angewandte Chemie 127 (42), pp. 12575 - 12580 (2015)

Vendrell Navarro, G.; Rúa, F.; Bujons, J.; Brockmeyer, A.; Janning, P.; Ziegler, S.; Messeguer, A.; Waldmann, H.: Positional Scanning Synthesis of a Peptoid Library Yields New Inducers of Apoptosis that Target Karyopherins and Tubulin. Chembiochem 16 (11), pp. 1580 - 1587 (2015)

Svenda, J.; Sheremet, M.; Kremer, L.; Maier, L.; Bauer, J. O.; Strohmann, C.; Ziegler, S.; Kumar, K.; Waldmann, H.: Biology-Oriented Synthesis of a Withanolide-Inspired Compound Collection Reveals Novel Modulators of Hedgehog Signaling. Angewandte Chemie International Edition 54 (19), pp. 5596 - 5602 (2015)

Svenda, J.; Sheremet, M.; Kremer, L.; Maier, L.; Bauer, J. O.; Strohmann, C.; Ziegler, S.; Kumar, K.; Waldmann, H.: Biology-Oriented Synthesis of a Withanolide-Inspired Compound Collection Reveals Novel Modulators of Hedgehog Signaling. Angewandte Chemie 127 (19), pp. 5688 - 5694 (2015)

Garcia Castro, M.; Kremer, L.; Reinkemeier, C. D.; Unkelbach, C.; Strohmann, C.; Ziegler, S.; Ostermann, C.; Kumar, K.: De novo branching cascades for structural and functional diversity in small molecules. Nature Communications 6 (3), 6516, pp. 1 - 13 (2015)

Akbulut, Y.; Gaunt, H. J.; Muraki, K.; Ludlow, M. J.; Amer, M. S.; Bruns, A.; Vasudev, N. S.; Radtke, L.; Willot, M.; Hahn, S. et al.; Seitz, T.; Ziegler, S.; Christmann, M.; Beech, D. J.; Waldmann, H.: (-)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels. Angewandte Chemie International Edition 54 (12), pp. 3787 - 3791 (2015)

Akbulut, Y.; Gaunt, H. J.; Muraki, K.; Ludlow, M. J.; Amer, M. S.; Bruns, A.; Vasudev, N. S.; Radtke, L.; Willot, M.; Hahn, S. et al.; Seitz, T.; Ziegler, S.; Christmann, M.; Beech, D. J.; Waldmann, H.: (−)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels. Angewandte Chemie 127 (12), pp. 3858 - 3862 (2015)

Tran, T. T. N.; Gerding-Reimers, C.; Schölermann, B.; Stanitzki, B.; Henkel, T.; Waldmann, H.; Ziegler, S.: Podoverine A-a novel microtubule destabilizing natural product from the Podophyllum species. Bioorganic & Medicinal Chemistry 22 (18), pp. 5110 - 5116 (2014)

Eschenbrenner, V.; Küchler, P.; Ziegler, S.; Kumar, K.; Waldmann, H.: An Enantioselective Inverse-Electron-Demand Imino Diels-Alder Reaction. Angewandte Chemie International Edition 53 (8), pp. 2134 - 2137 (2014)

Eschenbrenner, V.; Küchler, P.; Ziegler, S.; Kumar, K.; Waldmann, H.: An Enantioselective Inverse-Electron-Demand Imino Diels–Alder Reaction. Angewandte Chemie 126 (8), pp. 2166 - 2169 (2014)

Takayama, H.; Jia, Z.-J.; Kremer, L.; Bauer, J. O.; Strohmann, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Discovery of Inhibitors of the Wnt and Hedgehog Signaling Pathways through the Catalytic Enantioselective Synthesis of an Iridoid-Inspired Compound Collection. Angewandte Chemie - International Edition 52 (47), pp. 12404 - 12408 (2013)

Takayama, H.; Jia, Z.-J.; Kremer, L.; Bauer, J. O.; Strohmann, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Discovery of Inhibitors of the Wnt and Hedgehog Signaling Pathways through the Catalytic Enantioselective Synthesis of an Iridoid-Inspired Compound Collection. Angewandte Chemie 125 (47), Epub ahead of print; no final pagination, pp. 12630 - 12634 (2013)

Ziegler, S.; Pries, V.; Hedberg, C.; Waldmann, H.: Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack. Angewandte Chemie International Edition 52 (10), 1, pp. 2744 - 2792 (2013)

Ziegler, S.; Pries, V.; Hedberg, C.; Waldmann, H.: Identifizierung der Zielproteine bioaktiver Verbindungen: Die Suche nach der Nadel im Heuhaufen. Angewandte Chemie 125 (10), 1, pp. 2808 - 2859 (2013)

Zimmermann, T. J.; Roy, S.; Martinez, N. E.; Ziegler, S.; Hedberg, C.; Waldmann, H.: Biology-oriented synthesis of a tetrahydroisoquinoline-based compound collection targeting microtubule polymerization. ChemBioChem 14 (3), 1, pp. 295 - 300 (2013)

Voigt, T.; Gerding-Reimers, C.; Tran, T. T. N.; Bergmann, S.; Lachance, H.; Schölermann, B.; Brockmeyer, A.; Janning, P.; Ziegler, S.; Waldmann, H.: A Natural Product Inspired Tetrahydropyran Collection Yields Mitosis Modulators that Synergistically Target CSE1L and Tubulin. Angewandte Chemie International Edition 52 (1), 1, pp. 410 - 414 (2013)