Publications of Slava Ziegler

Hoock, J. G.; Burhop, A.; Greiner, L. C.; Schölermann, B.; Da Cruz Lopes Guita, C.; Liu, J.; Bag, S.; Pahl, A.; Sievers, S.; Scheel, R. et al.; Strohmann, C.; Ziegler, S.; Grigalunas, M.; Waldmann, H.: An Indole Dearomatization Strategy for the Synthesis of Pseudo-Natural Products. ChemBioChem: A European Journal of Chemical Biology (2025)

Rezaei Adariani, S.; Agne, D.; Koska, S.; Burhop, A.; Seitz, C.; Warmers, J.; Janning, P.; Metz, M.; Pahl, A.; Sievers, S. et al.; Waldmann, H.; Ziegler, S.: Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay. Journal of Medicinal Chemistry (2024)

Pahl, A.; Liu, J.; Patil, S.; Rezaei Adariani, S.; Schölermann, B.; Warmers, J.; Bonowski, J.; Koska, S.; Akbulut, Y.; Seitz, C. et al.; Sievers, S.; Ziegler, S.; Waldmann, H.: Illuminating Dark Chemical Matter Using the Cell Painting Assay. Journal of Medicinal Chemistry (2024)

Corkery, D.; Ursu, A.; Lucas, B.; Grigalunas, M.; Kriegler, S.; Oliva, R.; Dec, R.; Koska, S.; Pahl, A.; Sievers, S. et al.; Ziegler, S.; Winter, R.; Wu, Y.; Waldmann, H.: Inducin Triggers LC3-Lipidation and ESCRT-Mediated Lysosomal Membrane Repair. ChemBioChem: A European Journal of Chemical Biology (2023)

Xie, J.; Pahl, A.; Krzyzanowski, A.; Krupp, A.; Liu, J.; Koska, S.; Schölermann, B.; Zhang, R.; Bonowski, J.; Sievers, S. et al.; Strohmann, C.; Ziegler, S.; Grigalunas, M.; Waldmann, H.: Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space. Angewandte Chemie, International Edition in English (2023)

Wanner, D. M.; Becker, P. M.; Suhr, S.; Wannenmacher, N.; Ziegler, S.; Hermann, J.; Willig, F.; Gabler, J.; Jangid, K.; Schmid, J. et al.; Hans, A. C.; Frey, W.; Sarkar, B.; Kästner, J.; Peters, R.: Cooperative Lewis Acid-1,2,3-Triazolium-Aryloxide Catalysis: Pyrazolone Addition to Nitroolefins as Entry to Diaminoamides. Angewandte Chemie, International Edition in English (2023)

Pahl, A.; Schölermann, B.; Lampe, P.; Rusch, M.; Dow, M.; Hedberg, C.; Nelson, A.; Sievers, S.; Waldmann, H.; Ziegler, S.: Morphological subprofile analysis for bioactivity annotation of small molecules. Cell Chemical Biology (2023)

Flegel, J.; Shaaban, S.; Jia, Z.-J.; Schulte, B.; Lian, Y.; Krzyzanowski, A.; Metz, M.; Schneidewind, T.; Wesseler , F.; Flegel, A. et al.; Reich, A.; Brause, A.; Xue, G.; Zhang, M.; Dötsch, L.; Stender, I. D.; Hoffmann, J.-E.; Scheel, R.; Janning, P.; Rastinejad, F.; Schade, D.; Strohmann, C.; Antonchick, A. P.; Sievers, S.; Alves, P.; Ziegler, S.; Waldmann, H.: The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation. European Journal of Medicinal Chemistry (2022)

Schölermann, B.; Bonowski, J.; Grigalunas, M.; Burhop, A.; Xie, Y.; Hook, J.; Liu, J.; Nelson, A.; Dow, M.; Nowak, C. et al.; Pahl, A.; Sievers, S.; Ziegler, S.: Identification of Dihydroorotate Dehydrogenase Inhibitors using the Cell Painting Assay. ChemBioChem: A European Journal of Chemical Biology (2022)

Grigalunas, M.; Patil, S.; Krzyzanowski, A.; Pahl, A.; Flegel, J.; Schölermann, B.; Xie, J.; Sievers, S.; Ziegler, S.; Waldmann, H.: Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone. Chemistry – A European Journal (2022)

Akbarzadeh, M.; Deipenwisch, I.; Schoelermann, B.; Pahl, A.; Sievers, S.; Ziegler, S.; Waldmann, H.: Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds. Cell Chemical Biology, pp. 1053 - 1064 (2022)

Akbarzadeh, M.; Flegel, J.; Patil, S.; Shang, E.; Narayan, R.; Buchholzer, M.; Jasemi, N. S. K.; Grigalunas, M.; Krzyzanowski, A.; Abegg, D. et al.; Shuster, A.; Potowski, M.; Karatas, H.; Karageorgis, G.; Mosaddeghzadeh, N.; Zischinsky, M.-L.; Merten, C.; Golz, C.; Brieger, L.; Strohmann, C.; Antonchick, A. P.; Janning, P.; Adibekian, A.; Goody, R. S.; Ahmadian, M. R.; Ziegler, S.; Waldmann, H.: The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie International Edition, pp. 1 - 27 (2022)

Akbarzadeh, M.; Flegel, J.; Patil, S.; Shang, E.; Narayan, R.; Buchholzer, M.; Jasemi, N. S. K.; Grigalunas, M.; Krzyzanowski, A.; Abegg, D. et al.; Shuster, A.; Potowski, M.; Karatas, H.; Karageorgis, G.; Mosaddeghzadeh, N.; Zischinsky, M.-L.; Merten, C.; Golz, C.; Brieger, L.; Strohmann, C.; Antonchick, A. P.; Janning, P.; Adibekian, A.; Goody, R. S.; Ahmadian, M. R.; Ziegler, S.; Waldmann, H.: The Pseudo-Natural Product Rhonin Targets RHOGDI. Angewandte Chemie, pp. 1 - 27 (2022)

Akbarzadeh, M.; Deipenwisch, I.; Schoelermann, B.; Pahl, A.; Sievers, S.; Ziegler, S.; Waldmann, H.: Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds. Cell Chemical Biology, pp. 1 - 16 (2021)

Schneidewind, T.; Brause, A.; Schölermann, B.; Sievers, S.; Pahl, A.; Sankar, M. G.; Winzker, M.; Janning, P.; Kumar, K.; Ziegler, S. et al.; Waldmann, H.: Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis. Cell Chemical Biology 28 (12), pp. 1780 - 1794 (2021)

Hennes, E.; Lampe, P.; Dötsch, L.; Bruning, N.; Pulvermacher, L.-M.; Sievers, S.; Ziegler, S.; Waldmann, H.: Cell‐Based Identification of New IDO1 Modulator Chemotypes. Angewandte Chemie International Edition 60 (18), pp. 9869 - 9874 (2021)

Hennes, E.; Lampe, P.; Dötsch, L.; Bruning, N.; Pulvermacher, L.-M.; Sievers, S.; Ziegler, S.; Waldmann, H.: Cell-Based Identification of New IDO1 Modulator Chemotypes. Angewandte Chemie 133 (18), pp. 9957 - 9962 (2021)

Ziegler, S.; Sievers, S.; Waldmann, H.: Morphological profiling of small molecules. Cell Chemical Biology 28 (3), pp. 300 - 319 (2021)

Wilke, J.; Kawamura, T.; Xu, H.; Brause, A.; Friese, A.; Metz, M.; Schepmann, D.; Wünsch, B.; Artacho-Cordón, A.; Nieto, F. R. et al.; Watanabe, N.; Osada, H.; Ziegler, S.; Waldmann, H.: Discovery of a σ 1 receptor antagonist by combination of unbiased cell painting and thermal proteome profiling. Cell Chemical Biology 28, pp. 1 - 13 (2021)

Schneidewind, T.; Brause, A.; Pahl, A.; Burhop, A.; Mejuch, T.; Sievers, S.; Waldmann, H.; Ziegler, S.: Morphological profiling enables the identification of common mode of action for small molecules with different targets. Chembiochem 21 (22), pp. 3197 - 3207 (2020)