Publications of Herbert Waldmann

Shan, G.; Flegel, J.; Li, H.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors. Angewandte Chemie 130 (43), pp. 14446 - 14450 (2018)

Kaiser, N.; Mejuch, T.; Fedoryshchak, R.; Janning, P.; Tate, E. W.; Waldmann, H.: Photoactivatable Myristic Acid Probes for UNC119-Cargo Interactions. Chembiochem 20 (2), pp. 134 - 139 (2018)

Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P. et al.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H.: Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways. Cell Chemical Biology 25 (9), pp. 1095 - 1106 (2018)

Robke, L.; Rodrigues, T.; Schröder, P.; Foley, D. J.; Bernardes, G. J. L.; Laraia, L.; Waldmann, H.: Discovery of 2,4-dimethoxypyridines as novel autophagy inhibitors. Tetrahedron 74 (35), pp. 4531 - 4537 (2018)

Jia, Z.-J.; Takayama, H.; Futamura, Y.; Aono, H.; Bauer, J. O.; Strohmann, C.; Antonchick, A. P.; Osada, H.; Waldmann, H.: Catalytic Enantioselective Synthesis of a Pyrrolizidine-Alkaloid-Inspired Compound Collection with Antiplasmodial Activity. The Journal of Organic Chemistry 83 (13), pp. 7033 - 7041 (2018)

Cheung, S. Y.; Henrot, M.; Al-Saad, M.; Baumann, M.; Muller, H.; Unger, A.; Rubaiy, H. N.; Mathar, I.; Dinkel, K.; Nussbaumer, P. et al.; Klebl, B.; Freichel, M.; Rode, B.; Trainor, S.; Clapcote, S. J.; Christmann, M.; Waldmann, H.; Abbas, S. K.; Beech, D. J.; Vasudev, N. S.: TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A. Oncotarget 9 (51), pp. 29634 - 29643 (2018)

Erwin, N.; Dwivedi, M.; Mejuch, T.; Waldmann, H.; Winter, R.: UNC119A decreases the membrane-binding of myristoylated c-Src. ChemBioChem: A European Journal of Chemical Biology, pp. 1 - 7 (2018)

Laraia, L.; Robke, L.; Waldmann, H.: Bioactive Compound Collections: From Design to Target Identification. Chem 4 (4), pp. 705 - 730 (2018)

Pries, V.; Nöcker, C.; Khan, D.; Johnen, P.; Hong, Z.; Tripathi, A.; Keller, A.-L.; Fitz, M.; Perruccio, F.; Filipuzzi, I. et al.; Thavam, S.; Aust, T.; Riedl, R.; Ziegler, S.; Bono, F.; Schaaf, G.; Bankaitis, V. A.; Waldmann, H.; Hoepfner, D.: Target Identification and Mechanism of Action of Picolinamide and Benzamide Chemotypes with Antifungal Properties. Cell Chemical Biology 25 (3), pp. 279 - 290 (2018)

Rubaiy, H. N.; Seitz, T.; Hahn, S.; Choidas, A.; Habenberger, P.; Klebl, B.; Dinkel, K.; Nussbaumer, P.; Waldmann, H.; Christmann, M. et al.; Beech, D. J.: Identification of an (-)-englerin A analogue, which antagonizes (-)-englerin A at TRPC1/4/5 channels. British Journal of Pharmacology 175 (5), pp. 830 - 839 (2018)

Robke, L.; Futamura, Y.; Konstantinidis, G.; Wilke, J.; Aono, H.; Mahmoud, Z.; Watanabe, N.; Wu, Y.-W.; Osada, H.; Laraia, L. et al.; Waldmann, H.: Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chemical Science 9 (11), pp. 3014 - 3022 (2018)

Höing, S.; Yeh, T.-Y.; Baumann, M.; Martinez, N. E.; Habenberger , P.; Kremer, L.; Drexler, H. C. A.; Küchler, P.; Reinhardt, P.; Choidas, A. et al.; Zischinsky, M.-L.; Zischinsky, G.; Nandini, S.; Ledray, A. P.; Ketcham, S. A.; Reinhardt, L.; Abo-Rady, M.; Glatza, M.; King, S. J.; Nussbaumer, P.; Ziegler, S.; Klebl, B.; Schroer, T. A.; Schöler, H. R.; Waldmann, H.; Sterneckert, J.: Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein. Cell Chemical Biology 25, pp. 1 - 13 (2018)

Li, H.; Gontla, R.; Flegel, J.; Merten, C.; Ziegler, S.; Antonchick, A. P.; Waldmann, H.: Enantioselective Formal C(sp3 )-H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives. Angewandte Chemie 131 (1), pp. 313 - 317 (2018)

Muraki, K.; Ohnishi, K.; Takezawa, A.; Suzuki, H.; Hatano, N.; Muraki, Y.; Hamzah, N.; Foster, R.; Waldmann, H.; Nussbaumer, P. et al.; Christmann, M.; Bon, R. S.; Beech, D. J.: Na+ entry through heteromeric TRPC4/C1 channels mediates (-) Englerin A-induced cytotoxicity in synovial sarcoma cells. Scientific Reports 7:16988, 16988, pp. 1 - 12 (2017)

Jia, Z.-J.; Merten, C.; Knauer, L.; Murarka, S.; Strohmann, C.; Waldmann, H.: Biology-Oriented Synthesis of Decahydro-4,8-epoxyazulene Scaffolds. Synlett 28 (20), pp. 2918 - 2922 (2017)

Wilke, J.; Kawamura, T.; Watanabe, N.; Osada, H.; Ziegler, S.; Waldmann, H.: Identification of cytotoxic, glutathione-reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion. Bioorganic & Medicinal Chemistry 26 (8), pp. 1453 - 1461 (2017)

Lee, Y.-C.; Kumar, K.; Waldmann, H.: Ligand-directed Divergent Synthesis of Carbo- and Heterocyclic Ring Systems. Angewandte Chemie International Edition 57 (19), pp. 5212 - 5226 (2017)

Pahl, A.; Waldmann, H.; Kumar, K.: Exploring Natural Product Fragments for Drug and Probe Discovery. Chimia 71 (10), pp. 653 - 660 (2017)

Kremer, L.; Schultz-Fademrecht, C.; Baumann, M.; Habenberger, P.; Choidas, A.; Klebl, B.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Ziegler, S. et al.; Schneider, G.; Waldmann, H.: Discovery of a Novel Inhibitor of the Hedgehog Signaling Pathway through Cell-based Compound Discovery and Target Prediction. Angewandte Chemie International Edition 56 (42), pp. 13021 - 13025 (2017)

Plowright, A. T.; Ottmann, C.; Arkin, M.; Auberson, Y. P.; Timmerman, H.; Waldmann, H.: Joining Forces: The Chemical Biology-Medicinal Chemistry Continuum. Cell chemical biology 24 (9), pp. 1058 - 1065 (2017)