Publications of Daniel Rauh

Becker, C.; Öcal, S.; Nguyen, H. D.; Phan, T.; Keul, M.; Simard, J. R.; Rauh, D.: Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR. ChemBioChem: A European Journal of Chemical Biology 17 (11), pp. 990 - 994 (2016)

Fang, Z.; Simard, J. R.; Plenker, D.; Nguyen, H. D.; Phan, T.; Wolle, P.; Baumeister, S.; Rauh, D.: Discovery of Inter-Domain Stabilizers-A Novel Assay System for Allosteric Akt Inhibitors. ACS Chemical Biology 10 (1), pp. 279 - 288 (2015)

Richters, A.; Nguyen, H. D.; Phan, T.; Simard, J. R.; Grütter, C.; Engel, J.; Rauh, D.: Identification of Type II and III DDR2 Inhibitors. Journal of Medicinal Chemistry 57 (10), pp. 4252 - 4262 (2014)

Richters, A.; Ketzer, J.; Getlik, M.; Grütter, C.; Schneider, R.; Heuckmann, J. M.; Heynck, S.; Sos, M. L.; Gupta, A.; Unger, A. et al.; Schultz-Fademrecht, C.; Thomas, R. K.; Bauer, S.; Rauh, D.: Targeting Gain of Function and Resistance Mutations in Abl and KIT by Hybrid Compound Design. Journal of Medicinal Chemistry 56 (14), 1, pp. 5757 - 5772 (2013)

Schneider, R.; Gohla, A.; Simard, J. R.; Yadav, D. B.; Fang, Z.; van Otterlo, W. A. L.; Rauh, D.: Overcoming Compound Fluorescence in the FLiK Screening Assay with Red-Shifted Fluorophores. Journal of the American Chemical Society 135 (22), 1, pp. 8400 - 8408 (2013)

Schneider, R.; Beumer, C.; Simard, J. R.; Grütter, C.; Rauh, D.: Selective Detection of Allosteric Phosphatase Inhibitors. Journal of the American Chemical Society 135 (18), 1, pp. 6838 - 6841 (2013)

Over, B.; Wetzel, S.; Grütter, C.; Nakai, Y.; Renner, S.; Rauh, D.; Waldmann, H.: Natural-product-derived fragments for fragment-based ligand discovery. Nature Chemistry 5 (1), 1, pp. 21 - 28 (2013)

Sos, M. L.; Dietlein, F.; Peifer, M.; Schöttle, J.; Balke-Want, H.; Müller, C.; Koker, M.; Richters, A.; Heynck, S.; Malchers, F. et al.; Heuckmann, J. M.; Seidel, D.; Eyers, P. A.; Ullrich, R. T.; Antonchick, A. P.; Vintonyak, V. V.; Schneider, P. M.; Ninomiya, T.; Waldmann, H.; Büttner, R.; Rauh, D.; Heukamp, L. C.; Thomas, R. K.: A framework for identification of actionable cancer genome dependencies in small cell lung cancer. Proceedings of the National Academy of Sciences of the United States of America 109 (42), 1, pp. 17034 - 17039 (2012)

Getlik, M.; Simard, J. R.; Termathe, M.; Grütter, C.; Rabiller, M.; Van Otterlo, W. A. L.; Rauh, D.: Fluorophore Labeled Kinase Detects Ligands That Bind within the MAPK Insert of p38α Kinase. PLoS ONE 7 (7), 1, pp. e39713-1 - e39713-10 (2012)

Schneider, R.; Becker, C.; Simard, J. R.; Getlik, M.; Bohlke, N.; Janning, P.; Rauh, D.: Direct Binding Assay for the Detection of Type IV Allosteric Inhibitors of Abl. Journal of the American Chemical Society 134 (22), 1, pp. 9138 - 9141 (2012)

Grütter, C.; Simard, J. R.; Mayer-Wrangowski, S. C.; Schreier, P. H.; Pérez-Martín, J.; Richters, A.; Getlik, M.; Gutbrod, O.; Braun, C. A.; Beck, M. E. et al.; Rauh, D.: Targeting GSK3 from Ustilago maydis: Type-II Kinase Inhibitors as Potential Antifungals. ACS Chemical Biology 7 (7), 1, pp. 1257 - 1267 (2012)

Koch, A.; Rode, H. B.; Richters, A.; Rauh, D.; Hauf, S.: A Chemical Genetic Approach for Covalent Inhibition of Analogue-Sensitive Aurora Kinase. ACS Chemical Biology 7 (4), 1, pp. 723 - 731 (2012)

Antonchick, A. P.; Schuster, H.; Bruss, H.; Schürmann, M.; Preut, H.; Rauh, D.; Waldmann, H.: Enantioselective synthesis of the spirotryprostatin A scaffold. Tetrahedron 67 (52), 1, pp. 10195 - 10202 (2011)

Vintonyak, V. V.; Warburg, K.; Over, B.; Hübel, K.; Rauh, D.; Waldmann, H.: Identification and further development of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B. Tetrahedron 67 (35), 1, pp. 6713 - 6729 (2011)

Tückmantel, S.; Greul, J. N.; Janning, P.; Brockmeyer, A.; Grütter, C.; Simard, J. R.; Gutbrod, O.; Beck, M. E.; Tietjen, K.; Rauh, D. et al.; Schreier, P. H.: Identification of Ustilago maydis Aurora Kinase As a Novel Antifungal Target. Asc Chemical Biology 6 (9), 1, pp. 926 - 933 (2011)

Rode, H. B.; Sos, M. L.; Grütter, C.; Heynck, S.; Simard, J. R.; Rauh, D.: Synthesis and biological evaluation of 7-substituted-1-(3-bromophenylamino)isoquinoline-4-carbonitriles as inhibitors of myosin light chain kinase and epidermal growth factor receptor. Bioorganic & Medicinal Chemistry 19 (1), 1, pp. 429 - 439 (2011)

Vintonyak, V. V.; Waldmann, H.; Rauh, D.: Using small molecules to target protein phosphatases. Bioorganic & Medicinal Chemistry 19 (7), 1, pp. 2145 - 2155 (2011)

Klüter, S.; Simard, J. R.; Rode, H. B.; Grütter, C.; Pawar, V.; Raaijmakers, H. C. A.; Barf, T. A.; Rabiller, M.; van Otterlo, W. A. L.; Rauh, D.: Characterization of Irreversible Kinase Inhibitors by Directly Detecting Covalent Bond Formation: A Tool for Dissecting Kinase Drug Resistance. ChemBioChem 11 (18), 1, pp. 2557 - 2566 (2010)

Robubi, A.; Waldmann, H.; Rauh, D.: RAF Kinase Inhibitors in Cancer Treatment: Like a Bull in a China Shop? ChemBioChem 11 (12), 1, pp. 1645 - 1648 (2010)

Vintonyak, V. V.; Warburg, K.; Kruse, H.; Grimme, S.; Hübel, K.; Rauh, D.; Waldmann, H.: Identification of Thiazolidinones Spiro-Fused to Indolin-2-ones as Potent and Selective Inhibitors of the Mycobacterium tuberculosis Protein Tyrosine Phosphatase B. Angewandte Chemie 122 (34), 1, pp. 6038 - 6041 (2010)