Publications of Raphael Gasper

Pal, S.; Gordijenko, I.; Schmeink , S.; Somarghya, B.; Akbulut, Y.; Gasper, R.; `T Hart, P.: Stapled Peptides as Inhibitors of mRNA Deadenylation. Angewandte Chemie, International Edition in English (2024)

Borgelt, L.; Haacke, N.; Lampe, P.; Qiu, X.; Gasper, R.; Schiller, D.; Sievers, S.; Wu, P.: Small-molecule screening of ribonuclease L binders for RNA degradation. Biomedicine & Pharmacotherapy 154 (2023)

Scheming, S.; Amrahova, G.; Bigler, K.; Opney, J.; Pal, S.; Posada, L.; Gasper, R.; `T Hart, P.: Rationally designed stapled peptides allosterically inhibit PTBP1 RNA-binding. Chemical Science 14 (31) (2023)

Hwang, J.; Haacke, N.; Borgelt, L.; Qiu, X.; Gasper, R.; Wu, P.: Rational design and evaluation of 2-((pyrrol-2-yl)methylene)thiophen-4-ones as RNase L inhibitors. European Journal of Medicinal Chemistry (2023)

Davies, C.; Dötsch, L.; Ciulla, M. G.; Hennes, E.; Yoshida, K.; Gasper, R.; Scheel, R.; Sievers, S.; Strohmann, C.; Kumar, K. et al.; Ziegler, S.; Waldmann, H.: Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor Chemotype. Angewandte Chemie, International Edition in English (2022)

Hwang, J.; Qiu, X.; Borgelt, L.; Haacke, N.; Kanis, L.; Petroulia, S.; Gasper, R.; Schiller, D.; Lampe, P.; Sievers, S. et al.; Imig, J.; Wu, P.: Synthesis and evaluation of RNase L-binding 2-aminothiophenes as anticancer agents. Bioorganic & Medicinal Chemistry 58, 116653, pp. 1 - 15 (2022)

Niggemeyer, G.; Knyazeva, A.; Gasper, R.; Corkery, D.; Bodenbinder, P.-J.; Holstein, J. J.; Sievers, S.; Wu, Y.-W.; Waldmann, H.: Synthesis of 20-Membered Macrocyclic Pseudo-Natural Products Yields Inducers of LC3 Lipidation. Angewandte Chemie International Edition 61 (11), pp. 1 - 21 (2022)

Niggemeyer, G.; Knyazeva, A.; Gasper, R.; Corkery, D.; Bodenbinder, P.-J.; Holstein, J. J.; Sievers, S.; Wu, Y.-W.; Waldmann, H.: Synthesis of 20-Membered Macrocyclic Pseudo-Natural Products Yields Inducers of LC3 Lipidation. Angewandte Chemie 134 (11), pp. 1 - 21 (2022)

Fitzian, K.; Brückner, A.; Brohée, L.; Zech, R.; Antoni, C.; Kiontke, S.; Gasper, R.; Linard Matos, A. L.; Beel, S.; Wilhelm, S. et al.; Gerke, V.; Ungermann, C.; Nellist, M.; Raunser, S.; Demetriades, C.; Oeckinghaus, A.; Kümmel, D.: TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. Molecular Cell 81, pp. 1 - 26 (2021)

Krzyzanowski, A.; Gasper, R.; Adihou, H.; `T Hart, P.; Waldmann, H.: Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5-MEP50 Complex. Chembiochem 22 (11), pp. 1908 - 1914 (2021)

Adihou, H.; Gopalakrishnan, R.; Förster, T.; Guéret, S. M.; Gasper, R.; Geschwindner, S.; Carrillo García , C.; Karatas, H.; Pobbati, A. V.; Vazquez-Chantada, M. et al.; Davey, P.; Wassvik, C. M.; Pang, J. K. S.; Soh, B. S.; Hong, W.; Chiarparin, E.; Schade, D.; Plowright, A. T.; Valeur, E.; Lemurell, M.; Grossmann, T. N.; Waldmann, H.: A protein tertiary structure mimetic modulator of the Hippo signalling pathway. Nature Communications 11 (1), 5425, pp. 1 - 10 (2020)

Spinck, M.; Neumann-Staubitz, P.; Ecke, M.; Gasper, R.; Neumann, H.: Evolved, Selective Erasers of Distinct Lysine Acylations. Angewandte Chemie International Edition 59 (27), pp. 11142 - 11149 (2020)

Huwald, D.; Duda, S.; Gasper, R.; Olieric, V.; Hofmann, E.; Hemschemeier, A.: Distinctive structural properties of THB11, a pentacoordinate Chlamydomonas reinhardtii truncated hemoglobin with N- and C-terminal extensions. Journal of Biological Inorganic Chemistry 25 (2), pp. 267 - 283 (2020)

Spinck, M.; Neumann-Staubitz, P.; Ecke, M.; Gasper, R.; Neumann, H.: Evolvierte, selektive Eraser für spezifische Lysinacylierungen. Angewandte Chemie 132 (27), pp. 11236 - 11243 (2020)

Gasper, R.; Wittinghofer, A.: The Ras switch in structural and historical perspective. Biological Chemistry 401 (1), pp. 143 - 163 (2019)

Nass Kovacs, G.; Colletier, J.-P.; Grünbein, M. L.; Yang, Y.; Stensitzki, T.; Batyuk, A.; Carbajo, S.; Doak, R. B.; Ehrenberg, D.; Foucar, L. et al.; Gasper, R.; Gorel, A.; Hilpert, M.; Kloos, M.; Koglin, J. E.; Reinstein, J.; Roome, C. M.; Schlesinger, R.; Seaberg, M.; Shoeman, R. L.; Stricker, M.; Boutet, S.; Haacke, S.; Heberle, J.; Heyne, K.; Domratcheva, T.; Barends, T. R.M.; Schlichting, I.: Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin. Nature Communications 10 (1), 3177, pp. 1 - 17 (2019)

Rehic, E.; Hoenig, D.; Kamba, B. E.; Goehring, A.; Hofmann, E.; Gasper, R.; Matena, A.; Bayer, P.: Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei. Biomolecules 9 (3), pp. 1 - 20 (2019)