Publications of Petra Janning

Winzker, M.; Friese, A.; Koch, U.; Janning, P.; Ziegler, S.; Waldmann, H.: Development of a PDEδ targeting PROTAC that impairs lipid metabolism. Angewandte Chemie, International Edition 59 (14), pp. 5595 - 5601 (2019)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie, International Edition 59 (14), pp. 5721 - 5729 (2019)

Laraia, L.; Garivet, G.; Foley, D. J.; Kaiser, N.; Müller, S.; Zinken, S.; Pinkert, T.; Wilke, J.; Corkery, D.; Pahl, A. et al.; Sievers, S.; Janning, P.; Arenz, C.; Wu, Y.; Rodriguez, R.; Waldmann, H.: Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie 132 (14), pp. 5770 - 5778 (2019)

Lam, M. T.; Coppola, S.; Krumbach, O. H.F.; Prencipe, G.; Insalaco, A.; Cifaldi, C.; Brigida, I.; Zara, E.; Scala, S.; Di Cesare, S. et al.; Martinelli, S.; Di Rocco, M.; Pascarella, A.; Niceta, M.; Pantaleoni, F.; Ciolfi, A.; Netter, P.; Carisey, A. F.; Diehl, M.; Akbarzadeh, M.; Conti, F.; Merli, P.; Pastore, A.; Levi Mortera, S.; Camerini, S.; Farina, L.; Buchholzer, M.; Pannone, L.; Cao, T. N.; Coban-Akdemir, Z. H.; Jhangiani, S. N.; Muzny, D. M.; Gibbs, R. A.; Basso-Ricci, L.; Chiriaco, M.; Dvorsky, R.; Putignani, L.; Carsetti, R.; Janning, P.; Stray-Pedersen, A.; Erichsen, H. C.; Horne, A.; Bryceson, Y. T.; Torralba-Raga, L.; Ramme, K.; Rosti, V.; Bracaglia, C.; Messia, V.; Palma, P.; Finocchi, A.; Locatelli, F.; Chinn, I. K.; Lupski, J. R.; Mace, E. M.; Cancrini, C.; Aiuti, A.; Ahmadian, M. R.; Orange, J. S.; De Benedetti, F.; Tartaglia, M.: A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function. Journal of Experimental Medicine, pp. 1 - 22 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3. Angewandte Chemie, International Edition, pp. 1 - 28 (2019)

Ceballos, J.; Schwalfenberg, M.; Karageorgis, G.; Reckzeh, E. S.; Sievers, S.; Ostermann, C.; Pahl, A.; Sellstedt, M.; Nowacki, J.; Carnero Corrales, M. A. et al.; Wilke, J.; Laraia, L.; Tschapalda, K.; Metz, M.; Sehr, D. A.; Brand, S.; Winklhofer, K.; Janning, P.; Ziegler, S.; Waldmann, H.: Synthesis of Indomorphan Pseudo Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3. Angewandte Chemie, pp. 1 - 28 (2019)

Schulte-Zweckel, J.; Dwivedi, M.; Brockmeyer, A.; Janning, P.; Winter, R.; Triola, G.: A hydroxylamine probe for profiling S-acylated fatty acids on proteins. Chemical Communications, pp. 1 - 4 (2019)

Kremer, L.; Hennes, E.; Brause, A.; Ursu, A.; Robke, L.; Matsubayashi, H. T.; Nihongaki, Y.; Flegel, J.; Mejdrová, I.; Eickhoff, J. et al.; Baumann, M.; Nencka, R.; Janning, P.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Inoue, T.; Ziegler, S.; Waldmann, H.: Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie, International Edition, pp. 1 - 37 (2019)

Kremer, L.; Hennes, E.; Brause, A.; Ursu, A.; Robke, L.; Matsubayashi , H. T.; Nihongaki, Y.; Flegel, J.; Mejdrová, I.; Eickhoff, J. et al.; Baumann, M.; Nencka, R.; Janning, P.; Kordes, S.; Schöler, H. R.; Sterneckert, J.; Inoue, T.; Ziegler, S.; Waldmann, H.: Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß. Angewandte Chemie, pp. 1 - 37 (2019)

Laraia, L.; Friese, A.; Corkery, D. P.; Konstantinidis, G.; Erwin, N.; Hofer, W.; Karatas, H.; Klewer, L.; Brockmeyer, A.; Metz, M. et al.; Schölermann, B.; Dwivedi, M.; Li, L.; Rios-Munoz, P.; Köhn, M.; Winter, R.; Vetter, I. R.; Ziegler, S.; Janning, P.; Wu, Y.-W.; Waldmann, H.: The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nature Chemical Biology 15 (7), pp. 710 - 720 (2019)

Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie International Edition, pp. 1 - 14 (2019)

Friese, A.; Kapoor, S.; Schneidewind, T.; Rao Vidadala, S.; Sardana, J.; Brause, A.; Förster, T.; Bischoff, M.; Wagner, J.; Janning, P. et al.; Ziegler, S.; Waldmann, H.: Chemical genetics reveals a role of dCTP pyrophosphatase 1 in Wnt signaling. Angewandte Chemie, pp. 1 - 14 (2019)

Förster, T.; Shang, E.; Shimizu, K.; Sanada, E.; Schölermann, B.; Hübecker, M.; Hahne, G.; Pascual Lopez-Alberca, M.; Janning, P.; Watanabe, N. et al.; Sievers, S.; Giordanetto, F.; Shimizu, T.; Ziegler, S.; Osada, H.; Waldmann, H.: 2-Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation. European Journal of Organic Chemistry, pp. 1 - 12 (2019)

Uhlenbrock, N.; Smith, S.; Weisner, J.; Landel, I.; Lindemann, M.; Le, T. A.; Hardick, J.; Gontla, R.; Scheinpflug, R.; Czodrowski, P. et al.; Janning, P.; Depta, L.; Quambusch, L.; Müller, M. P.; Engels, B.; Rauh, D.: Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt. Chemical Science 10 (12), pp. 3573 - 3585 (2019)

Winzker, M.; Friese, A.; Koch, U.; Janning, P.; Ziegler, S.; Waldmann, H.: Development of a PDEd targeting PROTAC that impairs lipid metabolism. Angewandte Chemie 132 (14), pp. 5644 - 5650 (2019)

Schulte-Zweckel, J.; Schneidewind, T.; Abad, J. L.; Brockmeyer, A.; Janning, P.; Triola, G.: Azide-tagged sphingolipids for the proteome-wide identification of C16-ceramide-binding proteins. Chemical Communications 54 (97), pp. 13742 - 13745 (2018)

Kaiser, N.; Mejuch, T.; Fedoryshchak, R.; Janning, P.; Tate, E. W.; Waldmann, H.: Photoactivatable Myristic Acid Probes for UNC119-Cargo Interactions. Chembiochem 20 (2), pp. 134 - 139 (2018)

Brand, S.; Roy, S.; Schröder, P.; Rathmer, B.; Roos, J.; Kapoor, S.; Patil, S.; Pommerenke, C.; Maier, T.; Janning, P. et al.; Eberth, S.; Steinhilber, D.; Schade, D.; Schneider, G.; Kumar, K.; Ziegler, S.; Waldmann, H.: Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways. Cell Chemical Biology 25 (9), pp. 1095 - 1106 (2018)

Ulbrich, S.; Janning, P.; Seidel, R.; Matschke, J.; Gonsberg, A.; Jung, S.; Glatzel, M.; Engelhard, M.; Winklhofer, K. F.; Tatzelt, J.: Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease. PLoS One 13 (5), e0197659, pp. 1 - 15 (2018)

Koos, B.; Christmann, J.; Plettenberg, S.; Käding, D.; Becker, J.; Keteku, M.; Klein, C.; Imtiaz, S.; Janning, P.; Bastiaens, P. I. H. et al.; Wehner, F.: Hypertonicity-induced cation channels (HICCs) in HepG2 cells: architecture and role in proliferation vs. apoptosis. The Journal of Physiology - London, pp. 1 - 35 (2018)