Publications of Pascal Hommen

Borgelt, L.; Hohnen, L.; Hommen, P.; Goebel , G. L.; Liu, Y.; O'Mahony, G.; Wu, P.: N-Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28–Let-7 Interaction. ACS Medicinal Chemistry Letters (2023)

Hommen, P.; Hwang, J.; Huang, F.; Hohnen, L.; Wu, P.: Chromenopyrazole−Peptide Conjugates as Small-Molecule Based Inhibitors Disrupting the Protein−RNA Interaction of LIN28-let-7. ChemBioChem: A European Journal of Chemical Biology (2023)

Borgelt, L.; Huang, F.; Hohnen, L.; Qiu, X.; Goebel, G. L.; Hommen, P.; Wu, P.: Spirocyclic Chromenopyrazole Inhibitors Disrupting the Interaction between the RNA-Binding Protein LIN28 and Let-7. ChemBioChem: A European Journal of Chemical Biology (2023)

Goebel, G. L.; Hohnen, L.; Borgelt, L.; Hommen, P.; Qiu, X.; Lightfoot , H.; Wu, P.: Small molecules with tetrahydroquinoline-containing Povarov scaffolds as inhibitors disrupting the ProteineRNA interaction of LIN28elet-7. European Journal of Medicinal Chemistry 228, 114014, pp. 1 - 14 (2021)

Borgelt, L.; Li, F.; Hommen, P.; Lampe, P.; Hwang, J.; Goebel, G. L.; Sievers, S.; Wu, P.: Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein-RNA Interaction of LIN28 and Let-7. ACS Medicinal Chemistry Letters 12 (6), pp. 893 - 898 (2021)

`T Hart, P.; Hommen, P.; Noisier, A.; Krzyzanowski, A.; Schüler, D.; Porfetye, A. T.; Akbarzadeh, M.; Vetter, I. R.; Adihou, H.; Waldmann, H.: Structure based design of bicyclic peptide inhibitors of RbAp48. Angewandte Chemie International Edition 60 (4), pp. 1813 - 1820 (2020)

`T Hart, P.; Hommen, P.; Noisier, A.; Krzyzanowski, A.; Schüler, D.; Porfetye, A. T.; Akbarzadeh, M.; Vetter, I. R.; Adihou, H.; Waldmann, H.: Structure based design of bicyclic peptide inhibitors of RbAp48. Angewandte Chemie 133 (4), pp. 1841 - 1848 (2020)

Hommen, P.: Design, synthesis, and evaluation of small molecules and associated bifunctional conjugates targeting the Protein–RNA interaction of LIN28 and let-7. Dissertation, TU Dortmund, Dortmund (2023)