Journal Article (2956)
Journal Article
Aminothiazolone Inhibitors Disrupt the Protein–RNA Interaction of METTL16 and Modulate the m6A RNA Modification. JACS Au (2024)
Journal Article
Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Journal of Medicinal Chemistry (2024)
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Structure of the human KMN complex and implications for regulation of its assembly. Nature Structural & Molecular Biology (2024)
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A divergent intermediate strategy yields biologically diverse pseudo-natural products. Nature Chemistry (2024)
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N-Cyanopiperazines as Specific Covalent Inhibitors of the Deubiquitinating Enzyme UCHL1. Angewandte Chemie, International Edition in English (2024)
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Yersinia entomophaga Tc toxin is released by T10SS-dependent lysis of specialized cell subpopulations. Nature Microbiology (2024)
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Small molecule WDR5 inhibitors down-regulate lncRNA expression. RSC Medicinal Chemistry (2024)
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Exploiting π and Chalcogen Interactions for the β-Selective Glycosylation of Indoles through Glycal Conformational Distortion. Angewandte Chemie, International Edition in English (2023)
Journal Article
14 (1) (2023)
Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles. Nature Communications
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Structure and activation mechanism of the Makes caterpillars floppy 1 toxin. Nature Communications (2023)
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Cooperative Bifurcated Chalcogen Bonding and Hydrogen Bonding as Stereocontrolling Elements for Selective Strain-Release Septanosylation. Journal of the American Chemical Society (2023)
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Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype. Nature Communications (2023)
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RZZ-Spindly and CENP-E form an integrated platform to recruit dynein to the kinetochore corona. The EMBO Journal (2023)
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N-Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28–Let-7 Interaction. ACS Medicinal Chemistry Letters (2023)
Journal Article
Structure of the native myosin filament in the relaxed cardiac sarcomere. Nature (2023)